Interruptions of microsatellite sequences impact genome evolution and can alter disease
manifestation. However, human polymorphism levels at interrupted microsatellites (iMSs) …

Rapid advances in DNA sequencing and genotyping technologies are beginning to reveal
the scope and pattern of human genomic variation. Although single nucleotide …

Mutation rates of microsatellites vary greatly among loci. The causes of this heterogeneity
remain largely enigmatic yet are crucial for understanding numerous human neurological …

Microsatellites–a type of short tandem repeat (STR)–have been used for decades as
putatively neutral markers to study the genetic structure of diverse human populations …

Microsatellites—tandem repeats of short DNA motifs—are abundant in the human genome
and have high mutation rates. While microsatellite instability is implicated in numerous …

Mononucleotide microsatellites are tandem repeats of a single base pair, abundant within
coding exons and frequent sites of mutation in the human genome. Because the repeated …

A large majority of human microsatellite markers are longer than their homologues in
chimpanzees, suggesting that more expansion mutations have occurred in the lineage …

Microsatellite tandem repeats are frequent sites of strand slippage mutagenesis in the
human genome. Microsatellite mutations often occur as insertion/deletion of a repeat motif …

Dinucleotide microsatellites are dynamic DNA sequences that affect genome stability. Here,
we focused on mature microsatellites, defined as pure repeats of lengths above the …

The human genome harbors an abundance of repetitive DNA; however, its function
continues to be debated. Microsatellites—a class of short tandem repeat—are established …