[HTML][HTML] Autophagy in neurodegenerative diseases: from mechanism to therapeutic approach
J Nah, J Yuan, YK Jung - Molecules and cells, 2015 - Elsevier
Autophagy is a lysosome-dependent intracellular degradation process that allows recycling
of cytoplasmic constituents into bioenergetic and biosynthetic materials for maintenance of …
of cytoplasmic constituents into bioenergetic and biosynthetic materials for maintenance of …
Autophagy: The spotlight for cellular stress responses
Autophagy is an essential cellular mechanism which plays “housekeeping” role in normal
physiological processes including removing of long lived, aggregated and misfolded …
physiological processes including removing of long lived, aggregated and misfolded …
Molecular mechanism and regulation of autophagy1
Y YANG, Z LIANG, Z GU, Z QIN - Acta Pharmacologica Sinica, 2005 - Wiley Online Library
Autophagy is a major cellular pathway for the degradation of ong‐lived proteins and
cytoplasmic organelles in eukaryotic cells. A large number of intracellular/extracellular …
cytoplasmic organelles in eukaryotic cells. A large number of intracellular/extracellular …
[HTML][HTML] Autophagic pathways as new targets for cancer drug development
B Liu, Y Cheng, Q Liu, J Bao, JM Yang - Acta Pharmacologica Sinica, 2010 - nature.com
Autophagy is an evolutionarily conserved lysosomal self-digestion process involved in
degradation of long-lived proteins and damaged organelles. In recent years, increasing …
degradation of long-lived proteins and damaged organelles. In recent years, increasing …
[HTML][HTML] Targeting autophagy to overcome human diseases
Autophagy is an evolutionarily conserved cellular process, through which damaged
organelles and superfluous proteins are degraded, for maintaining the correct cellular …
organelles and superfluous proteins are degraded, for maintaining the correct cellular …
[HTML][HTML] Autophagy as a decisive process for cell death
S Jung, H Jeong, SW Yu - Experimental & molecular medicine, 2020 - nature.com
Autophagy is an intracellular catabolic pathway in which cellular constituents are engulfed
by autophagosomes and degraded upon autophagosome fusion with lysosomes …
by autophagosomes and degraded upon autophagosome fusion with lysosomes …
[HTML][HTML] Development of autophagy inducers in clinical medicine
Defects in autophagy have been linked to a wide range of medical illnesses, including
cancer as well as infectious, neurodegenerative, inflammatory, and metabolic diseases …
cancer as well as infectious, neurodegenerative, inflammatory, and metabolic diseases …
[HTML][HTML] Autophagy modulators: mechanistic aspects and drug delivery systems
Autophagy modulation is considered to be a promising programmed cell death mechanism
to prevent and cure a great number of disorders and diseases. The crucial step in designing …
to prevent and cure a great number of disorders and diseases. The crucial step in designing …
Chemical modulators of autophagy as biological probes and potential therapeutics
A Fleming, T Noda, T Yoshimori… - Nature chemical …, 2011 - nature.com
Autophagy is an evolutionarily conserved mechanism for protein degradation that is critical
for the maintenance of homeostasis in man. Autophagy has unexpected pleiotropic functions …
for the maintenance of homeostasis in man. Autophagy has unexpected pleiotropic functions …
Emerging potential of naturally occurring autophagy modulators against neurodegeneration
MA Rahman, MR Rahman, T Zaman… - Current …, 2020 - ingentaconnect.com
Background: Naturally-occurring products derived from living organisms have been shown
to modulate various pharmacological and biological activities. Natural products protect …
to modulate various pharmacological and biological activities. Natural products protect …