Autophagy is best known for its role in organelle and protein turnover, cell quality control,
and metabolism. The autophagic machinery has, however, also adapted to enable protein …

Autophagy refers to a ubiquitous set of catabolic pathways required to achieve proper
cellular homeostasis. Aberrant autophagy has been implicated in a multitude of diseases …

Autophagy (specifically macroautophagy) is an evolutionarily conserved catabolic process
where the cytoplasmic contents of a cell are sequestered within double membrane vacuoles …

Autophagy is a delicate intracellular degradation process that occurs due to diverse stressful
conditions, including the accumulation of damaged proteins and organelles as well as …

Protein silencing represents an essential tool in biomedical research. Targeted protein
degradation (TPD) strategies exemplified by PROTACs are rapidly emerging as modalities …

Autophagy is a tightly-regulated catabolic process of cellular self-digestion by which cellular
components are targeted to lysosomes for their degradation. Key functions of autophagy are …

Autophagy or self-eating is a complicated cellular process that is involved in protein and
organelle digestion occurring via a lysosome-dependent pathway. This process is of great …

Autophagy maintains cell, tissue and organism homeostasis through degradation. Complex
post-translational modulation of the Atg (autophagy-related) proteins adds additional entry …

Autophagy is the catabolic process by which the cell degrades cytoplasmic components
within lysosomes. 1 The balance between the biosynthesis of cellular components and their …

Autophagy and autophagy‐related processes are fundamentally important in human health
and disease. These processes are viewed primarily as cellular degradative pathways that …