Network types and their application in natural variation studies in plants

JM Jiménez-Gómez - Current opinion in plant biology, 2014 - Elsevier
Highlights•Networks are useful tools to integrate, display and analyze large sets of
information from multiple sources.•Network analyses help us observe global patterns of …

AraQTL – workbench and archive for systems genetics in Arabidopsis thaliana

H Nijveen, W Ligterink, JJB Keurentjes… - The Plant …, 2017 - Wiley Online Library
Genetical genomics studies uncover genome‐wide genetic interactions between genes and
their transcriptional regulators. High‐throughput measurement of gene expression in …

Identifying genetic variants underlying phenotypic variation in plants without complete genomes

Y Voichek, D Weigel - Nature genetics, 2020 - nature.com
Structural variants and presence/absence polymorphisms are common in plant genomes,
yet they are routinely overlooked in genome-wide association studies (GWAS). Here, we …

Mutation bias shapes gene evolution in Arabidopsis thaliana

JG Monroe, T Srikant, P Carbonell-Bejerano… - BioRxiv, 2020 - biorxiv.org
Classical evolutionary theory maintains that mutation rate variation between genes should
be random with respect to fitness–and evolutionary optimization of genic mutation rates …

[PDF][PDF] Statistical theory of phenotype abundance distributions: A test through exact enumeration of genotype spaces

JA Garcıa-Martın, P Catalán, S Manrubia… - Europhys …, 2018 - valbuena.fis.ucm.es
The evolutionary dynamics of molecular populations are strongly dependent on the structure
of genotype spaces. The map between genotype and phenotype determines how easily …

AraPheno: a public database for Arabidopsis thaliana phenotypes

Ü Seren, D Grimm, J Fitz, D Weigel… - Nucleic acids …, 2016 - academic.oup.com
Natural genetic variation makes it possible to discover evolutionary changes that have been
maintained in a population because they are advantageous. To understand genotype …

Network models for dissecting plant development by functional mapping

S Wu, JS Yap, Y Li, Q Li, G Fu, J Li, K Das… - Current …, 2009 - ingentaconnect.com
Understanding the genetic machinery of plant growth and development is of fundamental
importance in agriculture and biology. Recently, a novel statistical framework, coined …

Computational aspects underlying genome to phenome analysis in plants

AM Bolger, H Poorter, K Dumschott… - The Plant …, 2019 - Wiley Online Library
Recent advances in genomics technologies have greatly accelerated the progress in both
fundamental plant science and applied breeding research. Concurrently, high‐throughput …

[PDF][PDF] A min-cut solution to mapping phenotypes to networks of genetic markers

CA Azencott, D Grimm, Y Kawahara, KM Borgwardt - arXiv, 2012 - cazencott.info
As the increasing number of genome-wide association studies (GWAS) reveals the
limitations of analyses linking single genetic markers with phenotypic variation for explaining …

The Benefits of Permutation-Based Genome-Wide Association Studies

M John, A Korte, DG Grimm - Journal of Experimental Botany, 2024 - academic.oup.com
Linear mixed models (LMMs) are a commonly used method for genome-wide association
studies (GWAS) that aim to detect associations between genetic markers and phenotypic …