A New Catalog of Structural Variants in 1,301 A. thaliana Lines from Africa, Eurasia, and North America Reveals a Signature of Balancing Selection at Defense …

M Göktay, A Fulgione… - Molecular biology and …, 2021 - academic.oup.com
Genomic variation in the model plant Arabidopsis thaliana has been extensively used to
understand evolutionary processes in natural populations, mainly focusing on single …

Epistasis and Genetic Regulation of Variation in the Arabidopsis Metabolome

NA Eckardt - 2008 - academic.oup.com
Many factors contribute to genetic and phenotypic variation within an interbreeding
population. Phenotypic variation within a species or population is highly complex; it is often …

Adding levels of complexity enhances robustness and evolvability in a multilevel genotype–phenotype map

P Catalán, A Wagner, S Manrubia… - Journal of The Royal …, 2018 - royalsocietypublishing.org
Robustness and evolvability are the main properties that account for the stability and
accessibility of phenotypes. They have been studied in a number of computational genotype …

Genomic Rearrangements in Arabidopsis Considered as Quantitative Traits

M Imprialou, A Kahles, JG Steffen, EJ Osborne… - Genetics, 2017 - academic.oup.com
Structural Rearrangements can have unexpected effects on quantitative phenotypes.
Surprisingly, these rearrangements can also be considered as... To understand the …

Arabidopsis paves the way: genomic and network analyses in crops

T Ferrier, JT Matus, J Jin, JL Riechmann - Current Opinion in …, 2011 - Elsevier
Arabidopsis genomic and network analyses have facilitated crop research towards the
understanding of many biological processes of fundamental importance for agriculture …

[HTML][HTML] State-of-the-art technology and applications in crop phenomics

W Yang, JH Doonan, MJ Hawkesford… - Frontiers in Plant …, 2021 - frontiersin.org
Together with the rise of whole-genome sequencing of many plant species, large-scale and
high-throughput plant phenotyping (HTP), as well as associated phenotypic analysis, has …

Network theory for data-driven epistasis networks

CA Lareau, BA McKinney - Epistasis: Methods and Protocols, 2015 - Springer
One of the challenges of understanding the genetic basis of complex phenotypes is
explaining variability not attributable to individual genes. While most existing methods that …

[HTML][HTML] The utility of fitness landscapes and big data for predicting evolution

JAGM de Visser, SF Elena, I Fragata, S Matuszewski - Heredity, 2018 - nature.com
The prospect that we may be able to predict the outcome of future evolutionary processes
has motivated recent investigations of the factors that determine this predictability (Lässig et …

Genetic regulatory network motifs constrain adaptation through curvature in the landscape of mutational (co) variance

TD Hether, PA Hohenlohe - Evolution, 2014 - academic.oup.com
Abstract Systems biology is accumulating a wealth of understanding about the structure of
genetic regulatory networks, leading to a more complete picture of the complex genotype …

Genome-wide phylogenetic comparative analysis of plant transcriptional regulation: a timeline of loss, gain, expansion, and correlation with complexity

D Lang, B Weiche, G Timmerhaus… - Genome Biology and …, 2010 - academic.oup.com
Evolutionary retention of duplicated genes encoding transcription-associated proteins
(TAPs, comprising transcription factors and other transcriptional regulators) has been …