Autophagy is an essential, conserved lysosomal degradation pathway that controls the
quality of the cytoplasm by eliminating protein aggregates and damaged organelles. It …

Autophagy is an evolutionarily conserved cellular process, through which damaged
organelles and superfluous proteins are degraded, for maintaining the correct cellular …

Autophagy is a stress-induced cell survival program whereby cells under metabolic,
proteotoxic, or other stress remove dysfunctional organelles and/or misfolded …

Autophagy is a complex, physiological process devoted to degrade and recycle cellular
components. Proteins and organelles are first phagocytized by autophagosomes, then …

Autophagy, also known as macroautophagy, is a tightly regulated process involved in the
stress responses, such as starvation. It is a vacuolar, lysosomal pathway for the degradation …

Autophagy is an essential cellular mechanism which plays “housekeeping” role in normal
physiological processes including removing of long lived, aggregated and misfolded …

Macroautophagy/autophagy is an evolutionarily conserved pathway responsible for clearing
cytosolic aggregated proteins, damaged organelles or invading microorganisms …

Resistance of cancer cells to chemotherapy is a significant problem in oncology and the
development of sensitising agents or small-molecules with new mechanisms of action to kill …

Autophagy is an evolutionarily conserved lysosomal degradation pathway that eliminates
cytosolic proteins, macromolecules, organelles, and protein aggregates. Activation of …

Simple Summary The modulation of autophagy represents a potential therapeutic strategy
for cancer. More than one hundred clinical trials have been conducted or are ongoing to …