Autophagy is an evolutionarily conserved degradation pathway which primary functions as a
cell survival adaptive mechanism during stress conditions. Autophagy is a tumor suppressor …

Autophagy is being explored as a potential therapeutic target for enhancing the cytotoxic
effects of chemotherapeutic regimens in various malignancies. Autophagy plays a very …

Autophagy is a highly conserved catabolic and energy-generating process that facilitates the
degradation of damaged organelles or intracellular components, providing cells with …

Autophagy is best known for its role in organelle and protein turnover, cell quality control,
and metabolism. The autophagic machinery has, however, also adapted to enable protein …

Autophagy is an evolutionarily conserved intracellular catabolic process that is used by all
cells to degrade dysfunctional or unnecessary cytoplasmic components through delivery to …

Autophagy was originally described as a highly conserved system for the degradation of
cytosol through a lysosome-dependent pathway. In response to starvation, autophagy …

Autophagy serves a dichotomous role in cancer and recent advances have helped delineate
the appropriate settings where inhibiting or promoting autophagy may confer therapeutic …

Autophagy is a delicate intracellular degradation process that occurs due to diverse stressful
conditions, including the accumulation of damaged proteins and organelles as well as …

Genomic analysis of human cancers indicates that the loss or mutation of core autophagy
related genes,(ATG) is uncommon, whereas oncogenic events that activate autophagy and …

Autophagy is implicated in a wide range of (patho) physiological processes including
maintenance of cellular homeostasis, neurodegenerative disorders, aging and cancer. As …