Cardiomyopathies and genetic testing in heart failure: role in defining phenotype-targeted approaches and management

H Yogasundaram, W Alhumaid, T Dzwiniel… - Canadian Journal of …, 2021 - Elsevier
Cardiomyopathies represent an important cause of heart failure, often affecting young
individuals, and have important implications for relatives. Genetic testing for …

Implications of genetic testing in dilated cardiomyopathy

JAJ Verdonschot, MR Hazebroek… - Circulation: Genomic …, 2020 - Am Heart Assoc
Background: Genetic analysis is a first-tier test in dilated cardiomyopathy (DCM). Electrical
phenotypes are common in genetic DCM, but their exact contribution to the clinical course …

Genetics of paediatric cardiomyopathies

SM Ware - Current opinion in pediatrics, 2017 - journals.lww.com
Genetics is moving at a rapid pace in paediatric cardiomyopathy. Genetic testing is
increasingly being incorporated into clinical care. Although interpretation of rare genetic …

Genetics of dilated cardiomyopathy: risk of conduction defects and sudden cardiac death

S Arnous, P Syrris, S Sen-Chowdhry… - Cardiac …, 2010 - cardiacep.theclinics.com
Dilated cardiomyopathy (DCM) is a chronic progressive myocardial disorder with an annual
incidence of 6 to 8 cases/100,000 population and prevalence of 36.5 cases/100,000 …

Role of family history and clinical screening in the identification of families with idiopathic dilated cardiomyopathy in Johannesburg, South Africa

C Bailly, S Henriques, N Tsabedze… - South African Medical …, 2019 - journals.co.za
Background. Familial disease is implicated in 20-50% of cases of idiopathic dilated
cardiomyopathy (IDCM) worldwide. The contribution of familial factors to IDCM in the …

Inherited cardiomyopathies

H Raju, C Alberg, GS Sagoo, H Burton, ER Behr - Bmj, 2011 - bmj.com
Inherited cardiac conditions include primary electrical, myocardial, and structural heart
diseases, in addition to vascular conditions. The presentation, diagnosis, and management …

Genetic profiling for risk reduction in human cardiovascular disease

MJ Puckelwartz, EM McNally - Genes, 2014 - mdpi.com
Cardiovascular disease is a major health concern affecting over 80,000,000 people in the
US alone. Heart failure, cardiomyopathy, heart rhythm disorders, atherosclerosis and …

Genetics and clinics: together to diagnose cardiomyopathies

M Urtis, A Di Toro, R Osio, L Giuliani… - European Heart …, 2022 - academic.oup.com
The diagnostic paths of hereditary cardiomyopathies (CMPs) include both clinical and
molecular genetics. The first step is the clinical diagnosis that guides the decisions about …

Recent advances in the epidemiology, pathogenesis and prognosis of acute heart failure and cardiomyopathy in Africa

K Sliwa, BM Mayosi - Heart, 2013 - heart.bmj.com
This review addresses recent advances in the epidemiology, pathogenesis and prognosis of
acute heart failure and cardiomyopathy based on research conducted in Africa. We …

Genetic ideology of dilated cardiomyopathy

M Arad, H Lahat, D Freimark - Isr Med Assoc J, 2005 - ima.org.il
Familial cardiomyopathies represent a substantial portion of idiopathic dilated
cardiomyopathy in clinical practice. Diversity of clinical presentations and variability in …