Folic acid is vital for DNA synthesis and methylations through one-carbon (C1) metabolism.
Thus, it is essential for cell division during embryonic development. Although the oocytes …

Folic acid (vitamin B9) is the principal component of one-carbon (C1) metabolism in
mammalian cells. It acts as a coenzyme in C1 unit transfer during nucleotide and amino acid …

In mammalian reproduction, folic acid in the follicle environment has antioxidant properties
that can protect cells against oxidative stress. Dietary supplementation of folic acid affects …

Embryos that are produced in vitro frequently present epigenetic modifications. However,
maternal supplementation with folic acid (FA) may improve oocyte maturation and embryo …

Folic acid and glycine are factors of great importance in early gestation. In sows, folic acid
supplement can increase litter size through a decrease in embryonic mortality, while glycine …

The study aimed to evaluate the effect of folic acid supplementation on the maturation and
development of bovine oocytes and embryos in vitro, respectively. In Experiment 1, oocytes …

Maternal B-vitamin status at conception can affect fertility and the health of offspring. This
study details transcript expression for genes encoding key enzymes in the linked …

Improving the quality of oocytes matured in vitro is integral to enhancing the efficacy of in
vitro embryo production. Oxidative stress is one of the primary causes of quality decline in …

Folate, a cofactor for the supply of one‐carbon groups, is required by epigenetic processes
to regulate cell lineage determination during development. The intake of folic acid (FA), the …

Contents The development of mammalian pre‐implantation embryos is inhibited by heat
stress, and the inhibitory effect is associated with excess reactive oxygen species (ROS) …