Complex genetics and the etiology of human congenital heart disease
BD Gelb, WK Chung - Cold Spring …, 2014 - perspectivesinmedicine.cshlp.org
Congenital heart disease (CHD) is the most common birth defect. Despite considerable
advances in care, CHD remains a major contributor to newborn mortality and is associated …
advances in care, CHD remains a major contributor to newborn mortality and is associated …
Congenital heart disease: causes, diagnosis, symptoms, and treatments
RR Sun, M Liu, L Lu, Y Zheng, P Zhang - Cell biochemistry and biophysics, 2015 - Springer
The congenital heart disease includes abnormalities in heart structure that occur before
birth. Such defects occur in the fetus while it is developing in the uterus during pregnancy …
birth. Such defects occur in the fetus while it is developing in the uterus during pregnancy …
Epigenetics in congenital heart disease
Embryonic heart development is an intricate process that mainly involves morphogens,
transcription factors, and cardiac genes. The precise spatiotemporal expression of these …
transcription factors, and cardiac genes. The precise spatiotemporal expression of these …
Genetics of congenital heart disease: past and present
I Muntean, R Togănel, T Benedek - Biochemical genetics, 2017 - Springer
Congenital heart disease is the most common congenital anomaly, representing an
important cause of infant morbidity and mortality. Congenital heart disease represents a …
important cause of infant morbidity and mortality. Congenital heart disease represents a …
Personalized genetic diagnosis of congenital heart defects in newborns
OM Diz, R Toro, S Cesar, O Gomez… - Journal of Personalized …, 2021 - mdpi.com
Congenital heart disease is a group of pathologies characterized by structural malformations
of the heart or great vessels. These alterations occur during the embryonic period and are …
of the heart or great vessels. These alterations occur during the embryonic period and are …
The genetics of isolated congenital heart disease
SN Nees, WK Chung - … Journal of Medical Genetics Part C …, 2020 - Wiley Online Library
The genetic mechanisms underlying congenital heart disease (CHD) are complex and
remain incompletely understood. The majority of patients with CHD have an isolated heart …
remain incompletely understood. The majority of patients with CHD have an isolated heart …
[HTML][HTML] Navigating the non-coding genome in heart development and Congenital Heart Disease
Abstract Congenital Heart Disease (CHD) is characterised by a wide range of cardiac
defects, from mild to life-threatening, which occur in babies worldwide. To date, there is no …
defects, from mild to life-threatening, which occur in babies worldwide. To date, there is no …
The genetics of congenital heart disease: a review of recent developments
CG Weismann, BD Gelb - Current opinion in cardiology, 2007 - journals.lww.com
The recent knowledge about the molecular genetic causes of congenital heart disease is
reviewed. In many instances, these gene discoveries are being rapidly translated into …
reviewed. In many instances, these gene discoveries are being rapidly translated into …
Development gone awry: congenital heart disease
PJ Gruber, JA Epstein - Circulation research, 2004 - Am Heart Assoc
Significant advances in the understanding of the molecular and genetic basis of congenital
heart disease have emerged from gene inactivation studies in mice and from human genetic …
heart disease have emerged from gene inactivation studies in mice and from human genetic …
Charting the path: navigating embryonic development to potentially safeguard against congenital heart defects
J Bragança, R Pinto, B Silva, N Marques… - Journal of Personalized …, 2023 - mdpi.com
Congenital heart diseases (CHDs) are structural or functional defects present at birth due to
improper heart development. Current therapeutic approaches to treating severe CHDs are …
improper heart development. Current therapeutic approaches to treating severe CHDs are …