Improving recognition of antimicrobial peptides and target selectivity through machine learning and genetic programming
Growing bacterial resistance to antibiotics is spurring research on utilizing naturally-
occurring antimicrobial peptides (AMPs) as templates for novel drug design. While …
occurring antimicrobial peptides (AMPs) as templates for novel drug design. While …
Machine learning for antimicrobial peptide identification and design
Artificial intelligence (AI) and machine learning (ML) models are being deployed in many
domains of society and have recently reached the field of drug discovery. Given the …
domains of society and have recently reached the field of drug discovery. Given the …
Deep learning improves antimicrobial peptide recognition
Motivation Bacterial resistance to antibiotics is a growing concern. Antimicrobial peptides
(AMPs), natural components of innate immunity, are popular targets for developing new …
(AMPs), natural components of innate immunity, are popular targets for developing new …
Artificial intelligence-driven antimicrobial peptide discovery
P Szymczak, E Szczurek - Current Opinion in Structural Biology, 2023 - Elsevier
Antimicrobial peptides (AMPs) emerge as promising agents against antimicrobial resistance,
providing an alternative to conventional antibiotics. Artificial intelligence (AI) revolutionized …
providing an alternative to conventional antibiotics. Artificial intelligence (AI) revolutionized …
A generative approach toward precision antimicrobial peptide design
As the emergence of bacterial resistance is outpacing the development of new antibiotics,
we must find cost-effective and innovative approaches to discover new antibacterial …
we must find cost-effective and innovative approaches to discover new antibacterial …
Encodings and models for antimicrobial peptide classification for multi-resistant pathogens
S Spänig, D Heider - BioData Mining, 2019 - Springer
Antimicrobial peptides (AMPs) are part of the inherent immune system. In fact, they occur in
almost all organisms including, eg, plants, animals, and humans. Remarkably, they show …
almost all organisms including, eg, plants, animals, and humans. Remarkably, they show …
ABP-Finder: a tool to identify antibacterial peptides and the Gram-staining type of targeted bacteria
YB Ruiz-Blanco, G Agüero-Chapin, S Romero-Molina… - Antibiotics, 2022 - mdpi.com
Multi-drug resistance in bacteria is a major health problem worldwide. To overcome this
issue, new approaches allowing for the identification and development of antibacterial …
issue, new approaches allowing for the identification and development of antibacterial …
Deep learning regression model for antimicrobial peptide design
J Witten, Z Witten - BioRxiv, 2019 - biorxiv.org
Antimicrobial peptides (AMPs) are naturally occurring or synthetic peptides that show
promise for treating antibiotic-resistant pathogens. Machine learning techniques are …
promise for treating antibiotic-resistant pathogens. Machine learning techniques are …
Engineering selectively targeting antimicrobial peptides
The rise of antibiotic-resistant strains of bacterial pathogens has necessitated the
development of new therapeutics. Antimicrobial peptides (AMPs) are a class of compounds …
development of new therapeutics. Antimicrobial peptides (AMPs) are a class of compounds …
Antimicrobial peptides: an update on classifications and databases
Antimicrobial peptides (AMPs) are distributed across all kingdoms of life and are an
indispensable component of host defenses. They consist of predominantly short cationic …
indispensable component of host defenses. They consist of predominantly short cationic …
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