Hypertension (HTN) is a frequent condition with multifactorial cause in which genetic, fetal
and environmental factors interact to result in the final phenotype of blood pressure (BP) …

Hypertension has become a major global health burden due to its high prevalence and
associated increase in risk of cardiovascular disease and premature death. It is well …

In spite of recent successes for other complex diseases, essential hypertension has been
remarkably reluctant to reveal its underlying susceptibility genes through genomewide …

It has long been known that genetic factors play an important role in determining an
individualLs propensity to develop hypertension. In recent years, there has been major …

Estimated from family studies, the heritability of hypertension ranges from 31% to 68%.
Linkage studies and candidate gene association studies were once widely used to …

Background: Observational studies suggest higher glycated hemoglobin (HbA1c)
associated with higher hypertension risk although these associations could be confounded …

Hypertension, or elevated blood pressure, constitutes a major public health burden that
affects more than 1 billion people worldwide and contributes to~ 9 million deaths annually …

The genetics of blood pressure (BP) is all about discovery and understanding, but it is
certainly not for the faint hearted. Despite heroic effort, the question we posed nearly 15 …

Hypertension is a growing worldwide problem associated with an increased risk of
cardiovascular morbidity and mortality. However, the rates of prevalence of hypertension are …

This brief commentary is based on the debate that took part in May 2010 in New York. We
describe the initial difficulties experienced in early genome-wide association studies of …