Genome-wide association mapping and genomic prediction elucidate the genetic architecture of morphological traits in Arabidopsis

R Kooke, W Kruijer, R Bours, F Becker, A Kuhn… - Plant …, 2016 - academic.oup.com
Quantitative traits in plants are controlled by a large number of genes and their interaction
with the environment. To disentangle the genetic architecture of such traits, natural variation …

[引用][C] From genome to phenome: genome‐wide association studies and other approaches that bridge the genotype to phenotype gap

AR Fernie, J Gutierrez‐Marcos - The Plant Journal, 2019 - Wiley Online Library
Two of the most relevant technological innovations that in the last decade have resulted in
significant advances in plant science are the development of next-generation sequencing …

Genetic architecture of regulatory variation in Arabidopsis thaliana

X Zhang, AJ Cal, JO Borevitz - Genome research, 2011 - genome.cshlp.org
Studying the genetic regulation of expression variation is a key method to dissect complex
phenotypic traits. To examine the genetic architecture of regulatory variation in Arabidopsis …

Towards identifying genes underlying ecologically relevant traits in Arabidopsis thaliana

J Bergelson, F Roux - Nature Reviews Genetics, 2010 - nature.com
A major challenge in evolutionary biology and plant breeding is to identify the genetic basis
of complex quantitative traits, including those that contribute to adaptive variation. Here we …

Mapping the genetic basis of ecologically and evolutionarily relevant traits in Arabidopsis thaliana

PX Kover, R Mott - Current opinion in plant biology, 2012 - Elsevier
There has been a long standing interest in the relationship between genetic and phenotypic
variation in natural populations, in order to understand the genetic basis of adaptation and to …

Rational association of genes with traits using a genome-scale gene network for Arabidopsis thaliana

I Lee, B Ambaru, P Thakkar, EM Marcotte… - Nature …, 2010 - nature.com
We introduce a rational approach for associating genes with plant traits by combined use of
a genome-scale functional network and targeted reverse genetic screening. We present a …

A guide to genome‐wide association mapping in plants

LT Burghardt, ND Young, P Tiffin - Current Protocols in Plant …, 2017 - Wiley Online Library
Genome‐wide association studies (GWAS) have developed into a valuable approach for
identifying the genetic basis of phenotypic variation. In this article, we provide an overview of …

GWAPP: a web application for genome-wide association mapping in Arabidopsis

Ü Seren, BJ Vilhjálmsson, MW Horton, D Meng… - The Plant …, 2012 - academic.oup.com
Arabidopsis thaliana is an important model organism for understanding the genetics and
molecular biology of plants. Its highly selfing nature, small size, short generation time, small …

Environmental Adaptation Contributes to Gene Polymorphism across the Arabidopsis thaliana Genome

CR Lee, T Mitchell-Olds - Molecular biology and evolution, 2012 - academic.oup.com
The level of within-species polymorphism differs greatly among genes in a genome. Many
genomic studies have investigated the relationship between gene polymorphism and factors …

A Genome-Wide Association Analysis Reveals Epistatic Cancellation of Additive Genetic Variance for Root Length in Arabidopsis thaliana

J Lachowiec, X Shen, C Queitsch, Ö Carlborg - PLoS genetics, 2015 - journals.plos.org
Efforts to identify loci underlying complex traits generally assume that most genetic variance
is additive. Here, we examined the genetics of Arabidopsis thaliana root length and found …