The importance of rare variation in hypertension is unclear. The present study uses UK
biobank to analyse the association of rare coding variants to hypertension using gene …

Recent genome-wide association studies have identified genetic variants associated with
blood pressure (BP). We investigated whether genetic risk scores (GRSs) constructed of …

BACKGROUND: The Dietary Approaches to Stop Hypertension (DASH) diet score lowers
blood pressure (BP). We examined interactions between genotype and the DASH diet score …

High blood pressure (BP) remains the major heritable and modifiable risk factor for
cardiovascular disease. Persistent high BP, or hypertension, is a complex trait with both …

Type 2 diabetes, coronary artery disease and hypertension are associated with
anthropometric and biomarker traits, including waist-to-hip-ratio, body mass index and …

Objective To investigate the causal effect of protein intake on hypertension and the related
mediating pathways. Patients and Methods Using genome-wide association study summary …

Cardiovascular diseases are the leading cause of death worldwide. Essential hypertension
is a major risk factor for the development of other cardiovascular diseases and is caused by …

=+++++ 2. DNAm was adjusted for technical batch effects and blood-cell proportions, and
BP was averaged across the 52-min cardiovascular protocol. Y axes indicate the magnitude …

We present a Mendelian randomization (MR) pipeline (MeRP) to facilitate rapid, causal
inference analysis through automating key steps in developing and analyzing genetic …

Hypertension has become a major global health burden due to its high prevalence and
associated increase in risk of cardiovascular disease and premature death. It is well …