Combining NMR spectroscopy, transmission electron microscopy, biochemical and in vitro
toxicity assays, we characterized the effect of flavonoid glycosylation, a chemical …

Abstract β-Amyloid (Aβ) peptide, a major component of senile plaques has been regarded to
play a crucial role in the development and neuropathogenesis of Alzheimer's disease (AD) …

Epidemiological and preclinical studies indicate that polyphenol intake from moderate
consumption of red wines may lower the relative risk for developing Alzheimer's disease …

As natural functional bioactive ingredients found in foods and plants, polyphenols play
various antioxidant and anti-inflammatory roles to prevent the development of disease and …

Alzheimer's disease is a neurodegenerative disorder characterized by a decline in cognitive
function. The β-amyloid (Aβ) hypothesis suggests that Aβ peptides can spontaneously …

Alzheimer's disease (AD) is the most common neurodegenerative disease characterized by
cognitive decline and memory impairment. Many lines of evidence indicate that excessive β …

Brain ischemia is among the leading cause of death with majority of the cases are
associated with ischemic strokes. It can occur in two forms of either focal or global ischemia …

Alzheimer's disease (AD) is the most prevalent neurodegenerative disease of aging and
currently has no cure. Its onset and progression are influenced by multiple factors. There is …

Abstract Alzheimer's disease (AD), a complex neurodegenerative disorder causing multiple
cellular changes including impaired cholinergic system, beta‐amyloid (βA) aggregation, tau …

In this study natural-based complex polyphenols, obtained through a smart synthetic
approach, have been evaluated for their ability to inhibit the formation of Aβ42 oligomers, the …