Brain metastases (BM) occur frequently in many cancers, particularly non–small cell lung
cancer (NSCLC), breast cancer, and melanoma. The development of BM is associated with …

Brain metastases are significant causes of morbidity or mortality for patients with metastatic
cancer. With the application of novel systematic therapy and improvement of overall survival …

Brain metastases are one of the most feared complications of cancer, because even small
tumors may cause incapacitating neurologic symptoms. Surgical resection, often the major …

Brain metastasis is a major cause of systemic cancer morbidity and mortality. Many factors
participate in the development and maintenance of brain metastases. The survival of the …

The metastasis of cancer to the central nervous system (CNS) remains a devastating clinical
reality, carrying an estimated survival time of less than one year in spite of recent therapeutic …

Brain metastasis, which commonly arises in patients with lung cancer, breast cancer and
melanoma, is associated with poor survival outcomes and poses distinct clinical challenges …

Metastasis, involving the spread of systemic cancer to the brain, results in neurologic
disability and death. Current treatments are largely palliative in nature; improved therapeutic …

Brain metastases are a very common manifestation of cancer that have historically been
approached as a single disease entity given the uniform association with poor clinical …

The clinical management/understanding of brain metastases (BM) has changed
substantially in the last 5 years, with key advances and clinical trials highlighted in this …

Brain metastases occur commonly in patients with advanced solid malignancies. Yet, less is
known about brain metastases than cancer-related entities of similar incidence. Advances in …