Autophagy and cancer therapy
Y Kondo, S Kondo - Autophagy, 2006 - Taylor & Francis
Autophagy is a dynamic process of protein degradation which is typically observed during
nutrient deprivation. Recently, interest in autophagy has been renewed among oncologists …
nutrient deprivation. Recently, interest in autophagy has been renewed among oncologists …
[HTML][HTML] Autophagy-related signaling pathways are involved in cancer
C Chen, H Gao, X Su - Experimental and Therapeutic …, 2021 - spandidos-publications.com
Autophagy is a self-digestion process in cells that can maintain energy homeostasis under
normal circumstances. However, misfolded proteins, damaged mitochondria and other …
normal circumstances. However, misfolded proteins, damaged mitochondria and other …
The multifaceted role of autophagy in cancer and the microenvironment
H Folkerts, S Hilgendorf, E Vellenga… - Medicinal research …, 2019 - Wiley Online Library
Autophagy is a crucial recycling process that is increasingly being recognized as an
important factor in cancer initiation, cancer (stem) cell maintenance as well as the …
important factor in cancer initiation, cancer (stem) cell maintenance as well as the …
The role of autophagy in cancer
N Santana-Codina, JD Mancias… - Annual Review of …, 2017 - annualreviews.org
Autophagy is a highly conserved and regulated process that targets proteins and damaged
organelles for lysosomal degradation to maintain cell metabolism, genomic integrity, and …
organelles for lysosomal degradation to maintain cell metabolism, genomic integrity, and …
Targeting the pro-death and pro-survival functions of autophagy as novel therapeutic strategies in cancer
Autophagy is an evolutionarily conserved lysosomal pathway for degrading cytoplasmic
proteins, macromolecules, and organelles. While autophagy has become one of the most …
proteins, macromolecules, and organelles. While autophagy has become one of the most …
[HTML][HTML] Autophagy modulation: a prudent approach in cancer treatment?
E Bishop, TD Bradshaw - Cancer chemotherapy and pharmacology, 2018 - Springer
Autophagy is a tightly controlled process comprising lysosomal degradation and recycling of
cellular proteins and organelles. In cancer, its paradoxical dual role of cytoprotection and …
cellular proteins and organelles. In cancer, its paradoxical dual role of cytoprotection and …
Autophagy and cancer therapy
P Maycotte, A Thorburn - Cancer biology & therapy, 2011 - Taylor & Francis
Although autophagy has been shown to have a clear role as a tumor suppressor
mechanism, its role in cancer treatment is still controversial. Because autophagy is a survival …
mechanism, its role in cancer treatment is still controversial. Because autophagy is a survival …
[HTML][HTML] The paradox of autophagy and its implication in cancer etiology and therapy
A Eisenberg-Lerner, A Kimchi - Apoptosis, 2009 - Springer
Autophagy is a cellular self-catabolic process in which cytoplasmic constituents are
sequestered in double membrane vesicles that fuse with lysosomes where they are …
sequestered in double membrane vesicles that fuse with lysosomes where they are …
Targeting autophagy in cancer
JMM Levy, CG Towers, A Thorburn - Nature Reviews Cancer, 2017 - nature.com
Autophagy is a mechanism by which cellular material is delivered to lysosomes for
degradation, leading to the basal turnover of cell components and providing energy and …
degradation, leading to the basal turnover of cell components and providing energy and …