Paradoxical roles of autophagy in different stages of tumorigenesis: protector for normal or cancer cells
Autophagy serves as a dynamic degradation and recycling system that provides biological
materials and energy in response to stress. The role of autophagy in tumor development is …
materials and energy in response to stress. The role of autophagy in tumor development is …
The role of autophagy in tumour development and cancer therapy
MT Rosenfeldt, KM Ryan - Expert reviews in molecular medicine, 2009 - cambridge.org
Autophagy is a catabolic membrane-trafficking process that leads to sequestration and
degradation of intracellular material within lysosomes. It is executed at basal levels in every …
degradation of intracellular material within lysosomes. It is executed at basal levels in every …
Autophagy and chemotherapy resistance: a promising therapeutic target for cancer treatment
X Sui, R Chen, Z Wang, Z Huang, N Kong… - Cell death & …, 2013 - nature.com
Induction of cell death and inhibition of cell survival are the main principles of cancer
therapy. Resistance to chemotherapeutic agents is a major problem in oncology, which …
therapy. Resistance to chemotherapeutic agents is a major problem in oncology, which …
Autophagy and the cell cycle: a complex landscape
SG Mathiassen, D De Zio, F Cecconi - Frontiers in oncology, 2017 - frontiersin.org
Autophagy is a self-degradation pathway, in which cytoplasmic material is sequestered in
double-membrane vesicles and delivered to the lysosome for degradation. Under basal …
double-membrane vesicles and delivered to the lysosome for degradation. Under basal …
The autophagic paradox in cancer therapy
WKK Wu, SB Coffelt, CH Cho, XJ Wang, CW Lee… - Oncogene, 2012 - nature.com
Autophagy, hallmarked by the formation of double-membrane bound organelles known as
autophagosomes, is a lysosome-dependent pathway for protein degradation. The role of …
autophagosomes, is a lysosome-dependent pathway for protein degradation. The role of …
Autophagy and tumorigenesis
S Roy, J Debnath - Seminars in immunopathology, 2010 - Springer
Autophagy, a catabolic process involved in the sequestration and lysosomal degradation of
cytoplasmic contents, is crucial for cellular homeostasis. The current literature supports that …
cytoplasmic contents, is crucial for cellular homeostasis. The current literature supports that …
Autophagy and cancer therapy
A Thorburn, DH Thamm, DL Gustafson - Molecular pharmacology, 2014 - ASPET
Autophagy is the process by which cellular material is delivered to lysosomes for
degradation and recycling. There are three different types of autophagy, but …
degradation and recycling. There are three different types of autophagy, but …
Deconvoluting the context-dependent role for autophagy in cancer
E White - Nature reviews cancer, 2012 - nature.com
Autophagy (also known as macroautophagy) captures intracellular components in
autophagosomes and delivers them to lysosomes, where they are degraded and recycled …
autophagosomes and delivers them to lysosomes, where they are degraded and recycled …
[HTML][HTML] A perspective on the role of autophagy in cancer
Autophagy refers to a ubiquitous set of catabolic pathways required to achieve proper
cellular homeostasis. Aberrant autophagy has been implicated in a multitude of diseases …
cellular homeostasis. Aberrant autophagy has been implicated in a multitude of diseases …
The multifaceted role of autophagy in cancer
RC Russell, KL Guan - The EMBO journal, 2022 - embopress.org
Autophagy is a cellular degradative pathway that plays diverse roles in maintaining cellular
homeostasis. Cellular stress caused by starvation, organelle damage, or proteotoxic …
homeostasis. Cellular stress caused by starvation, organelle damage, or proteotoxic …