Inflammation and immune mechanisms are crucially involved in the pathophysiology of the
development, acute damage cascades, and chronic course after ischemic stroke …

The immune response to stroke is an exciting target for future stroke therapies. Stroke is a
leading cause of morbidity and mortality worldwide, and clot removal (mechanical or …

Recent clinical and experimental studies have highlighted a complex role for the immune
system in the pathophysiological changes that occur after acute stroke. Sensors of the innate …

Following a cerebral ischemic event, substantial alterations in both cellular and molecular
activities occur due to ischemia-induced cerebral pathology. Mounting evidence indicates …

Immune cells can significantly predict and affect the clinical outcome of stroke. In particular,
the neutrophil‐to‐lymphocyte ratio was shown to predict hemorrhagic transformation and the …

The secondary neuroinflammatory response has come into focus of experimental stroke
research. Immunological mechanisms after acute stroke are being investigated in the hope …

Stroke is a major cause of morbidity and mortality, and activation of the immune system can
impact on stroke outcome. Although the majority of research has focused on the role of the …

Stroke is one of the leading causes of death and disability worldwide. The long‐standing
dogma that stroke is exclusively a vascular disease has been questioned by extensive …

Despite the enormous progress in the understanding of the course of the ischemic stroke
over the last few decades, a therapy that effectively protects neurovascular units (NVUs) and …

Stroke is the second leading cause of death worldwide and a leading cause of disability.
Most strokes are caused by occlusion of a major cerebral artery, and substantial advances …