Despite extensive research into stroke pathology, there have not been any major recent
advancements in stroke therapeutics. Animal models of cerebral ischemia and clinical data …

Immune and inflammatory responses actively modulate the pathophysiological processes of
acute brain injuries such as stroke. Soon after the onset of stroke, signals such as brain …

Stroke is one of the leading causes of death and disability worldwide. The long‐standing
dogma that stroke is exclusively a vascular disease has been questioned by extensive …

Modulation of the Postischemic Immune Response to Improve Stroke Outcome | Stroke Science
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The profound damage to the CNS caused by ischemic lesions has been well documented.
Yet, relatively little is known about the contribution to and effects on the immune system …

The nervous and immune systems control whole-body homeostasis and respond to various
types of tissue injury, including stroke, in a coordinated manner. Cerebral ischaemia and …

Background and Purpose: Stroke is a major cause of chronic neurological disability. There is
considerable interest in understanding how acute transcriptome changes evolve into …

It is currently well established that the immune system is activated in response to transient or
focal cerebral ischemia. This acute immune activation occurs in response to damage, and …

The immune response to stroke is an exciting target for future stroke therapies. Stroke is a
leading cause of morbidity and mortality worldwide, and clot removal (mechanical or …

The inflammatory and immunological responses play a significant role after stroke. The
innate immune activation stimulated by microglia during stroke results in the migration of …