[HTML][HTML] Autophagy modulators in cancer therapy
K Buzun, A Gornowicz, R Lesyk, K Bielawski… - International Journal of …, 2021 - mdpi.com
Autophagy is a process of self-degradation that plays an important role in removing
damaged proteins, organelles or cellular fragments from the cell. Under stressful conditions …
damaged proteins, organelles or cellular fragments from the cell. Under stressful conditions …
Understanding autophagy in cell death control
F Platini, R Perez-Tomas, S Ambrosio… - Current …, 2010 - ingentaconnect.com
Autophagy is an evolutionarily conserved degradation pathway which primary functions as a
cell survival adaptive mechanism during stress conditions. Autophagy is a tumor suppressor …
cell survival adaptive mechanism during stress conditions. Autophagy is a tumor suppressor …
Autophagy as a molecular target for cancer treatment
Autophagy is an evolutionarily conserved catabolic mechanism, by which eukaryotic cells
recycle or degrades internal constituents through membrane-trafficking pathway. Thus …
recycle or degrades internal constituents through membrane-trafficking pathway. Thus …
[HTML][HTML] Autophagy dysfunctions associated with cancer cells and their therapeutic implications
A Udristioiu, D Nica-Badea - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Genomic analysis of human cancers indicates that the loss or mutation of core autophagy
related genes,(ATG) is uncommon, whereas oncogenic events that activate autophagy and …
related genes,(ATG) is uncommon, whereas oncogenic events that activate autophagy and …
Cell survival and cell death at the intersection of autophagy and apoptosis: Implications for current and future cancer therapeutics
N Bata, NDP Cosford - ACS pharmacology & translational science, 2021 - ACS Publications
Autophagy and apoptosis are functionally distinct mechanisms for cytoplasmic and cellular
turnover. While these two pathways are distinct, they can also regulate each other, and …
turnover. While these two pathways are distinct, they can also regulate each other, and …
Autophagy: Molecular mechanisms and their implications for anticancer therapies
S Meschini, M Condello, P Lista… - Current cancer drug …, 2011 - ingentaconnect.com
Autophagy is a catabolic process whereby cells maintain homeostasis by eliminating
unnecessary proteins and damaged organelles. It may be triggered under physiological …
unnecessary proteins and damaged organelles. It may be triggered under physiological …
Autophagy and cancer: Basic mechanisms and inhibitor development
Y Hama, Y Ogasawara, NN Noda - Cancer Science, 2023 - Wiley Online Library
Autophagy is a lysosomal degradation system of cytoplasmic components that contributes to
cellular homeostasis through the turnover of various biomolecules and organelles, often in a …
cellular homeostasis through the turnover of various biomolecules and organelles, often in a …
Pharmacological inhibitors of autophagy as novel cancer therapeutic agents
Autophagy is an evolutionarily conserved cellular degradative process in which intracellular
components (cellular proteins and organelles) are engulfed in autophagosomes which then …
components (cellular proteins and organelles) are engulfed in autophagosomes which then …
Autophagy regulators as potential cancer therapeutic agents: a review
S Li, L Wang, Y Hu, R Sheng - Current topics in medicinal …, 2015 - ingentaconnect.com
Autophagy is an important basic metabolic mechanism by engulfing and degrading the
unnecessary or dysfunctional cellular components within double-membered autolysosomes …
unnecessary or dysfunctional cellular components within double-membered autolysosomes …
Molecular machinery of autophagy and its implication in cancer
Y Li, J Zhang, T Liu, Y Chen, X Zeng, X Chen… - The American journal of …, 2012 - Elsevier
Autophagy is an intracellular lysosome-dependent catabolic process that is indispensable
for maintaining cellular homeostasis through the turnover and elimination of defective or …
for maintaining cellular homeostasis through the turnover and elimination of defective or …