Autophagy is a highly conserved catabolic and energy-generating process that facilitates the
degradation of damaged organelles or intracellular components, providing cells with …

Autophagy is an evolutionarily conserved catabolic mechanism, by which eukaryotic cells
recycle or degrades internal constituents through membrane-trafficking pathway. Thus …

Autophagy is being explored as a potential therapeutic target for enhancing the cytotoxic
effects of chemotherapeutic regimens in various malignancies. Autophagy plays a very …

In the last two decades, accumulating evidence pointed to the importance of autophagy in
various human diseases. As an essential evolutionary catabolic process of cytoplasmatic …

Autophagy is a catabolic program that is responsible for the degradation of dysfunctional or
unnecessary proteins and organelles to maintain cellular homeostasis. Mechanistically, it …

Autophagy is a lysosomal degradation system of cytoplasmic components that contributes to
cellular homeostasis through the turnover of various biomolecules and organelles, often in a …

Autophagy serves a dichotomous role in cancer and recent advances have helped delineate
the appropriate settings where inhibiting or promoting autophagy may confer therapeutic …

Simple Summary Autophagy is the capability of cells to dismantle and recycle parts of
themselves. This process is closely intertwined with other crucial cell functions, such as …

Autophagy is intricately linked with many intracellular signaling pathways, particularly
nutrient-sensing mechanisms and cell death signaling cascades. In cancer, the roles of …

Macroautophagy (referred to hereafter as autophagy) is a highly regulated cellular process
that serves to remove damaged proteins and organelles from the cell. Autophagy contributes …