DNA synthesis and methylations are crucial during pre-implantation embryonic
development, and are mediated by one-carbon metabolism of folates. Folates, transported …

Folate is essential for DNA synthesis and methylation via one‐carbon (C1) metabolism
during embryonic development. It is transported into the developing oocytes via folate …

Folic acid is vital for DNA synthesis and methylations through one-carbon (C1) metabolism.
Thus, it is essential for cell division during embryonic development. Although the oocytes …

Endogenous folate stores are required in preimplantation embryos of several species, but
how folates are accumulated and whether they can be replenished has not been …

The folate cycle is central to cellular one-carbon metabolism, where folates are carriers of
one-carbon units that are critical for synthesis of purines, thymidylate, and S …

Maternal B-vitamin status at conception can affect fertility and the health of offspring. This
study details transcript expression for genes encoding key enzymes in the linked …

It is well understood that maternal folate deficiency can cause abnormal fetal development.
However, the extent to which placental development and function are also dependent upon …

Folate is an essential micronutrient during pregnancy. The differential expression of genes
related to folate transport and metabolism during the advancing gestation and pregnancy …

Introduction Folates are essential nutrients for fetal development and pregnancy outcomes;
they are transported to the fetus during gestation through specific folate transporters located …

Folate transporters, including the reduced folate carrier and the proton-coupled folate
transporter, encoded by Slc19a1 and Slc46a1 genes respectively, play important roles in the …