Prognostic biomarkers associated with immune checkpoint inhibitors in hepatocellular carcinoma

X Chen, L Kou, X Xie, S Su, J Li, Y Li - Immunology, 2024 - Wiley Online Library
The treatment of hepatocellular carcinoma (HCC), particularly advanced HCC, has been a
serious challenge. Immune checkpoint inhibitors (ICIs) are landmark drugs in the field of …

Immune checkpoint inhibitors in hepatocellular carcinoma: current strategies and biomarkers predicting response and/or resistance

F Pelizzaro, F Farinati, F Trevisani - Biomedicines, 2023 - mdpi.com
In recent years, immune checkpoint inhibitors (ICIs) have revolutionized the treatment of
patients with hepatocellular carcinoma (HCC). Following the positive results of the …

[HTML][HTML] Biochemical predictors of response to immune checkpoint inhibitors in unresectable hepatocellular carcinoma

A Rizzo, G Brandi - Cancer treatment and research communications, 2021 - Elsevier
Hepatocellular carcinoma (HCC) represents the most commonly diagnosed liver cancer
worldwide, and the overall survival of patients with unresectable disease is poor. In the last …

Predictive biomarkers for checkpoint inhibitor-based immunotherapy in hepatocellular carcinoma: where do we stand?

A Rizzo, AD Ricci, A Di Federico, G Frega… - Frontiers in …, 2021 - frontiersin.org
Hepatocellular carcinoma (HCC) remains the sixth most commonly diagnosed malignancy
worldwide, still representing an important cause of cancer-related death. Over the next few …

Which role for predictors of response to immune checkpoint inhibitors in hepatocellular carcinoma?

A Rizzo, A Cusmai, G Gadaleta-Caldarola… - Expert review of …, 2022 - Taylor & Francis
Introduction Hepatocellular carcinoma (HCC) remains a frequently diagnosed malignancy
worldwide, still representing an important cause of cancer-related death. Recent years have …

[HTML][HTML] Heterogeneous responses in hepatocellular carcinoma: the achilles heel of immune checkpoint inhibitors

Z Lin, D Lu, X Wei, J Wang, X Xu - American journal of cancer …, 2020 - ncbi.nlm.nih.gov
Abstract Treatment of patients with hepatocellular carcinoma (HCC) remains a serious
challenge due to high heterogeneity and limited treatment options. In the past few decades …

Monitoring immune checkpoint regulators as predictive biomarkers in hepatocellular carcinoma

R Shrestha, P Prithviraj, M Anaka, KR Bridle… - Frontiers in …, 2018 - frontiersin.org
The global burden of hepatocellular carcinoma (HCC), one of the frequent causes of cancer-
related deaths worldwide, is rapidly increasing partly due to the limited treatment options …

[HTML][HTML] Predictive Biomarkers of Immune Checkpoint Inhibitor-Based Mono-and Combination Therapies for Hepatocellular Carcinoma

LB Jeng, J Wang, CF Teng - Journal of Cancer, 2024 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is among the most frequent and deadly human cancers
worldwide. It has been shown that interaction between immune checkpoint receptors and …

Biomarkers predicting the efficacy of immune checkpoint inhibitors in hepatocellular carcinoma

R Qin, T Jin, F Xu - Frontiers in Immunology, 2023 - frontiersin.org
In recent years, immune checkpoint inhibitors (ICIs) have emerged as a transformative
approach in treating advanced hepatocellular carcinoma (HCC). Despite their success …

Lessons from immune checkpoint inhibitor trials in hepatocellular carcinoma

R Mohr, F Jost-Brinkmann, B Özdirik… - Frontiers in …, 2021 - frontiersin.org
The implementation of immune checkpoint inhibitors (ICI) into the clinical management of
different malignancies has largely changed our understanding of cancer treatment. After …