[HTML][HTML] Prediction of antimicrobial peptides toxicity based on their physico-chemical properties using machine learning techniques

H Khabbaz, MH Karimi-Jafari, AA Saboury… - BMC bioinformatics, 2021 - Springer
Background Antimicrobial peptides are promising tools to fight against ever-growing
antibiotic resistance. However, despite many advantages, their toxicity to mammalian cells is …

[HTML][HTML] Prediction of antimicrobial peptides based on sequence alignment and feature selection methods

P Wang, L Hu, G Liu, N Jiang, X Chen, J Xu, W Zheng… - PloS one, 2011 - journals.plos.org
Antimicrobial peptides (AMPs) represent a class of natural peptides that form a part of the
innate immune system, and this kind of 'nature's antibiotics' is quite promising for solving the …

A cumulative strategy to predict and characterize antimicrobial peptides (AMPs) from protein database

G Ravichandran, V Kumaresan, P Bhatt… - International Journal of …, 2017 - Springer
Antimicrobial peptides (AMPs) are indivisible part of the innate immune system in
invertebrates. AMPs have been proven to have crucial role with a wide range of biological …

[HTML][HTML] Prediction of linear cationic antimicrobial peptides active against gram-negative and gram-positive bacteria based on machine learning models

ÜG Söylemez, M Yousef, Z Kesmen, ME Büyükkiraz… - Applied Sciences, 2022 - mdpi.com
Antimicrobial peptides (AMPs) are considered as promising alternatives to conventional
antibiotics in order to overcome the growing problems of antibiotic resistance …

Knowledge-based computational methods for identifying or designing novel, non-homologous antimicrobial peptides

D Juretić, D Vukičević, D Petrov, M Novković… - European biophysics …, 2011 - Springer
We describe computational approaches for identifying promising lead candidates for the
development of peptide antibiotics, in the context of quantitative structure–activity …

Application of 'HESH'descriptors for the structure-activity relationships of antimicrobial peptides

M Shu, Y Jiang, L Yang, Y Wu, H Mei… - Protein and Peptide …, 2009 - ingentaconnect.com
In this paper, HESH, which was a new set of amino acid descriptors including Hydrophobic,
Electronic, Steric and Hydrogen bond contribution properties, were derived from multi …

AI4AMP: an antimicrobial Peptide predictor using physicochemical property-Based encoding method and deep learning

TT Lin, LY Yang, IH Lu, WC Cheng, ZR Hsu, SH Chen… - Msystems, 2021 - Am Soc Microbiol
Antimicrobial peptides (AMPs) are innate immune components that have recently stimulated
considerable interest among drug developers due to their potential as antibiotic substitutes …

ADAPTABLE: A comprehensive web platform of antimicrobial peptides tailored to the user's research

F Ramos-Martín, T Annaval, S Buchoux… - Life science …, 2019 - life-science-alliance.org
Antimicrobial peptides (AMPs) are part of the innate immune response to pathogens in all of
the kingdoms of life. They have received significant attention because of their extraordinary …

PyAMPA: a high-throughput prediction and optimization tool for antimicrobial peptides

M Ramos-Llorens, R Bello-Madruga, J Valle… - …, 2024 - journals.asm.org
The alarming rise of antibiotic-resistant bacterial infections is driving efforts to develop
alternatives to conventional antibiotics. In this context, antimicrobial peptides (AMPs) have …

Discovering new in silico tools for antimicrobial peptide prediction

M Torrent, M Victoria Nogues, E Boix - Current drug targets, 2012 - ingentaconnect.com
Antimicrobial peptides (AMPs) are important effectors of the innate immune system and play
a vital role in the prevention of infections. Due to the increased emergence of new antibiotic …