E-CLEAP: An ensemble learning model for efficient and accurate identification of antimicrobial peptides
SC Wang - Plos one, 2024 - journals.plos.org
With the increasing problem of antimicrobial drug resistance, the search for new
antimicrobial agents has become a crucial task in the field of medicine. Antimicrobial …
antimicrobial agents has become a crucial task in the field of medicine. Antimicrobial …
An efficient evaluation system accelerates α-helical antimicrobial peptide discovery and its application to global human genome mining
L Liu, C Wang, M Zhang, Z Zhang, Y Wu… - Frontiers in …, 2022 - frontiersin.org
Antimicrobial peptides (AMPs), as an important part of the innate immune system of an
organism, is a kind of promising drug candidate for novel antibiotics due to their unique …
organism, is a kind of promising drug candidate for novel antibiotics due to their unique …
Peptide array based discovery of synthetic antimicrobial peptides
CW Diehnelt - Frontiers in microbiology, 2013 - frontiersin.org
The rise of antibiotic resistance has emphasized the shortcomings in antibiotic drug
development (Boucher et al., 2013). The move from biological based discovery methods to …
development (Boucher et al., 2013). The move from biological based discovery methods to …
Optimization of antibacterial peptides by genetic algorithms and cheminformatics
Pathogens resistant to available drug therapies are a pressing global health problem. Short,
cationic peptides represent a novel class of agents that have lower rates of drug resistance …
cationic peptides represent a novel class of agents that have lower rates of drug resistance …
AniAMPpred: artificial intelligence guided discovery of novel antimicrobial peptides in animal kingdom
R Sharma, S Shrivastava, S Kumar Singh… - Briefings in …, 2021 - academic.oup.com
With advancements in genomics, there has been substantial reduction in the cost and time
of genome sequencing and has resulted in lot of data in genome databases. Antimicrobial …
of genome sequencing and has resulted in lot of data in genome databases. Antimicrobial …
Creation of new antimicrobial peptides
OV Galzitskaya - International Journal of Molecular Sciences, 2023 - mdpi.com
Antimicrobial peptides (AMPs) are natural compounds that exhibit potent antimicrobial
activity against various microorganisms, including bacteria, fungi, and viruses. However, the …
activity against various microorganisms, including bacteria, fungi, and viruses. However, the …
Structure–activity predictions from computational mining of protein databases to assist modular design of antimicrobial peptides
Antimicrobial peptides (AMPs) are naturally produced by pro-and eukaryotes and are
promising alternatives to antibiotics to fight multidrug-resistant microorganisms. However …
promising alternatives to antibiotics to fight multidrug-resistant microorganisms. However …
Computer-aided design of antimicrobial peptides: are we generating effective drug candidates?
MH Cardoso, RQ Orozco, SB Rezende… - Frontiers in …, 2020 - frontiersin.org
Antimicrobial peptides (AMPs), especially antibacterial peptides, have been widely
investigated as potential alternatives to antibiotic-based therapies. Indeed, naturally …
investigated as potential alternatives to antibiotic-based therapies. Indeed, naturally …
Antimicrobial peptide resistance and scope of computational biology in antimicrobial peptide research
CKV Ramesan, NV Vinod, S Skariyachan - Antimicrobial Peptides, 2023 - Elsevier
The different antimicrobial peptides (AMPs) isolated from various sources vary in their amino
acid numbers and net charge, are recognized by nucleic acid sequencing. Since the …
acid numbers and net charge, are recognized by nucleic acid sequencing. Since the …
AMPFinder: A computational model to identify antimicrobial peptides and their functions based on sequence-derived information
S Yang, Z Yang, X Ni - Analytical Biochemistry, 2023 - Elsevier
Antimicrobial peptides (AMPs) called host defense peptides have existed among all classes
of life with 5–100 amino acids generally and can kill mycobacteria, envelop viruses …
of life with 5–100 amino acids generally and can kill mycobacteria, envelop viruses …