Targeting autophagy using natural compounds for cancer prevention and therapy
S Deng, MK Shanmugam, AP Kumar, CT Yap, G Sethi… - Cancer, 2019 - Wiley Online Library
Autophagy, also known as macroautophagy, is a tightly regulated process involved in the
stress responses, such as starvation. It is a vacuolar, lysosomal pathway for the degradation …
stress responses, such as starvation. It is a vacuolar, lysosomal pathway for the degradation …
Molecular insights into the multifunctional role of natural compounds: autophagy modulation and cancer prevention
Autophagy is a vacuolar, lysosomal degradation pathway for injured and damaged protein
molecules and organelles in eukaryotic cells, which is controlled by nutrients and stress …
molecules and organelles in eukaryotic cells, which is controlled by nutrients and stress …
Phytochemicals as potent modulators of autophagy for cancer therapy
MA Moosavi, A Haghi, M Rahmati, H Taniguchi… - Cancer Letters, 2018 - Elsevier
The dysregulation of autophagy is involved in the pathogenesis of a broad range of
diseases, and accordingly universal research efforts have focused on exploring novel …
diseases, and accordingly universal research efforts have focused on exploring novel …
Therapeutic targeting of autophagy in disease: biology and pharmacology
Y Cheng, X Ren, WN Hait, JM Yang - Pharmacological reviews, 2013 - ASPET
Autophagy, a process of self-digestion of the cytoplasm and organelles through which
cellular components are recycled for reuse or energy production, is an evolutionarily …
cellular components are recycled for reuse or energy production, is an evolutionarily …
New visions on natural products and cancer therapy: autophagy and related regulatory pathways
Simple Summary In the past few years, clinical as well as regular scientists have been
paying attention to medicinal applications of natural products. There are several …
paying attention to medicinal applications of natural products. There are several …
Autophagy modulation as a target for anticancer drug discovery
X Li, H Xu, Y Liu, N An, S Zhao, J Bao - Acta Pharmacologica Sinica, 2013 - nature.com
Autophagy, an evolutionarily conserved catabolic process involving the engulfment and
degradation of non-essential or abnormal cellular organelles and proteins, is crucial for …
degradation of non-essential or abnormal cellular organelles and proteins, is crucial for …
Autophagy in cancer: regulation by small molecules
AS Limpert, LJ Lambert, NA Bakas, N Bata… - Trends in …, 2018 - cell.com
During times of stress, autophagy is a cellular process that enables cells to reclaim
damaged components by a controlled recycling pathway. This mechanism for cellular …
damaged components by a controlled recycling pathway. This mechanism for cellular …
Pharmacological inhibitors of autophagy as novel cancer therapeutic agents
Autophagy is an evolutionarily conserved cellular degradative process in which intracellular
components (cellular proteins and organelles) are engulfed in autophagosomes which then …
components (cellular proteins and organelles) are engulfed in autophagosomes which then …
Autophagy: The spotlight for cellular stress responses
Autophagy is an essential cellular mechanism which plays “housekeeping” role in normal
physiological processes including removing of long lived, aggregated and misfolded …
physiological processes including removing of long lived, aggregated and misfolded …
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