Background: Deviations from the optimal vancomycin dosing may occur in the neonatal and
pediatric population due to inconsistencies in the recommended dosing algorithms. This …

Background Vancomycin is a frequently used antibiotic in neonates. However, there is no
consensus guideline on the optimal dosing regimen and therapeutic drug monitoring (TDM) …

Background Vancomycin is an antibiotic that is widely used in pediatric intensive care, but
the safe and effective use of this drug is challenging. Objective This study aimed to assess …

Background Vancomycin is used to treat serious gram-positive infections in neonates.
Currently, there is no consensus on the preferred empiric dosing regimen or target trough …

Aims Vancomycin is frequently used in critically ill children in whom the drug
pharmacokinetics are significantly altered as a result of changes in renal clearance and …

Background There is no consensus on vancomycin dosing in newborns and young infants.
Objective The first objective was to assess the efficiency of a simplified dosing regimen with …

Background: Therapeutic drug monitoring (TDM) is routinely used for optimization of
vancomycin therapy, because of exposure-related efficacy and toxicity, in addition to …

Background Empiric vancomycin dosing regimens fail to achieve recommended target
trough concentrations of 10-20 mg/L in the majority of infants. This study assessed the …

Introduction: Vancomycin remains the reference antibiotic in neonates for care-related
infections caused by ß-lactam–resistant Gram-positive bacteria. Achieving the optimal serum …

Background Methicillin-resistant Staphylococcus aureus (MRSA) infections among children
are escalating annually. Vancomycin stands as the frontline therapeutic agent against …