Glymphatic imaging using MRI

T Taoka, S Naganawa - Journal of Magnetic Resonance …, 2020 - Wiley Online Library
In recent years, the existence of a mass transport system in the brain via cerebrospinal fluid
(CSF) or interstitial fluid (ISF) has been suggested by many studies. The glymphatic system …

Noninvasive magnetic resonance imaging measures of glymphatic system activity

K Kamagata, Y Saito, C Andica… - Journal of Magnetic …, 2024 - Wiley Online Library
The comprehension of the glymphatic system, a postulated mechanism responsible for the
removal of interstitial solutes within the central nervous system (CNS), has witnessed …

Glymphatic MRI in idiopathic normal pressure hydrocephalus

G Ringstad, SAS Vatnehol, PK Eide - Brain, 2017 - academic.oup.com
The glymphatic system has in previous studies been shown as fundamental to clearance of
waste metabolites from the brain interstitial space, and is proposed to be instrumental in …

Current concepts in intracranial interstitial fluid transport and the glymphatic system: part II—imaging techniques and clinical applications

JM Klostranec, D Vucevic, KD Bhatia, HGJ Kortman… - Radiology, 2021 - pubs.rsna.org
The glymphatic system is a recently discovered network unique to the central nervous
system that allows for dynamic exchange of interstitial fluid (ISF) and cerebrospinal fluid …

[HTML][HTML] The glymphatic system in humans: investigations with magnetic resonance imaging

S Naganawa, T Taoka, R Ito… - Investigative …, 2024 - journals.lww.com
The concept of the glymphatic system was proposed more than a decade ago as a
mechanism for interstitial fluid flow and waste removal in the central nervous system. The …

[HTML][HTML] Non-invasive imaging of CSF-mediated brain clearance pathways via assessment of perivascular fluid movement with diffusion tensor MRI

IF Harrison, B Siow, AB Akilo, PG Evans, O Ismail… - Elife, 2018 - elifesciences.org
The glymphatics system describes a CSF-mediated clearance pathway for the removal of
potentially harmful molecules, such as amyloid beta, from the brain. As such, its components …

Mapping of CSF transport using high spatiotemporal resolution dynamic contrast‐enhanced MRI in mice: effect of anesthesia

EH Stanton, NDÅ Persson, RS Gomolka… - Magnetic …, 2021 - Wiley Online Library
Purpose Dynamic contrast‐enhanced MRI (DCE‐MRI) represents the only available
approach for glymphatic cerebrospinal fluid (CSF) flow 3D mapping in the brain of living …

MRI with intrathecal MRI gadolinium contrast medium administration: a possible method to assess glymphatic function in human brain

PK Eide, G Ringstad - Acta radiologica open, 2015 - journals.sagepub.com
Recently, the “glymphatic system” of the brain has been discovered in rodents, which is a
paravascular, transparenchymal route for clearance of excess brain metabolites and …

The glymphatic system: a review of the challenges in visualizing its structure and function with MR imaging

S Naganawa, T Taoka - Magnetic Resonance in Medical Sciences, 2022 - jstage.jst.go.jp
The central nervous system (CNS) was previously thought to be the only organ system
lacking lymphatic vessels to remove waste products from the interstitial space. Recently …

Delayed clearance of cerebrospinal fluid tracer from entorhinal cortex in idiopathic normal pressure hydrocephalus: a glymphatic magnetic resonance imaging study

PK Eide, G Ringstad - Journal of Cerebral Blood Flow & …, 2019 - journals.sagepub.com
The glymphatic system plays a key role for clearance of waste solutes from the rodent brain.
We recently found evidence of glymphatic circulation in the human brain when using …