A review on exosomes application in clinical trials: perspective, questions, and challenges

J Rezaie, M Feghhi, T Etemadi - Cell Communication and Signaling, 2022 - Springer
Background Exosomes are progressively known as significant mediators of cell-to-cell
communication. They convey active biomolecules to target cells and have vital functions in …

[HTML][HTML] A review on exosome-based cancer therapy

A Von Schulze, F Deng - Journal of Cancer Metastasis and …, 2020 - oaepublish.com
Cancer is one of the leading causes of mortality and morbidity globally. Many types of
cancer treatments have been developed, such as chemotherapy, surgery, radiotherapy, and …

Biological function of exosomes as diagnostic markers and therapeutic delivery vehicles in carcinogenesis and infectious diseases

BJ Crenshaw, B Sims, QL Matthews - Nanomedicines, 2018 - books.google.com
Exosomes are nano-sized vesicles that are formed during inward budding of multivesicular
bodies and the maturation of endosomes. They are secreted by almost all cell types under …

[HTML][HTML] Tumor-derived exosome promotes metastasis via altering its phenotype and inclusions

Y Zhou, F Chen, X Xie, H Nie, S Lian, C Zhong… - Journal of …, 2021 - ncbi.nlm.nih.gov
Although tumor-derived exosomes play an important role in the process of metastasis,
differences in exosomes secreted by the same cells at different stages or conditions have …

Tumor-derived exosomes in cancer metastasis risk diagnosis and metastasis therapy

S Jiang, C Hu, P Liu, M Lu - Clinical and Translational Oncology, 2019 - Springer
Exosomes are endosomes secreted from the membrane by exocytosis as multivesicular
bodies and are generally defined by their spherical, unilamellar morphology, size and the …

Exosome-based strategies for diagnosis and therapy of glioma cancer

M Karami Fath, J Azami, A Masoudi… - Cancer cell …, 2022 - Springer
Glioblastoma belongs to the most aggressive type of cancer with a low survival rate that is
characterized by the ability in forming a highly immunosuppressive tumor microenvironment …

Exosome-based smart drug delivery tool for cancer theranostics

R Kar, R Dhar, S Mukherjee, S Nag… - ACS biomaterials …, 2023 - ACS Publications
Exosomes are the phospholipid-membrane-bound subpopulation of extracellular vesicles
derived from the plasma membrane. The main activity of exosomes is cellular …

Exosome-mediated immunosuppression in tumor microenvironments

QH Xie, JQ Zheng, JY Ding, YF Wu, L Liu, ZL Yu… - Cells, 2022 - mdpi.com
Exosomes are membranous structures secreted by nearly all cell types. As critical
messengers for intercellular communication, exosomes deliver bioactive cargoes to …

Exosome-mediated crosstalk between tumor cells and innate immune cells: implications for cancer progression and therapeutic strategies

LB Kwantwi - Journal of cancer research and clinical oncology, 2023 - Springer
The increasing number of cancer-associated deaths despite the substantial improvement in
diagnosis and treatment has sparked discussions on the need for novel biomarkers and …

[HTML][HTML] Exosomes derived from cancerous and non-cancerous cells regulate the anti-tumor response in the tumor microenvironment

S Bae, J Brumbaugh, B Bonavida - Genes & cancer, 2018 - ncbi.nlm.nih.gov
The tumor microenvironment (TME) is a unique platform of cancer biology that considers the
local cellular environment in which a tumor exists. Increasing evidence points to the TME as …