The first annual workshop for preclinical and clinical development of radiosensitizers took
place at the National Cancer Institute on August 8–9, 2012. Radiotherapy is one of the most …

Radiation therapy is a highly effective cancer treatment modality, and extensive
investigations have been undertaken over the years to augment its efficacy in the clinic. This …

The development of molecular targeted drugs with radiation and chemotherapy is critically
important for improving the outcomes of patients with hard-to-treat, potentially curable …

There is a growing appreciation of the potential value of combining novel molecularly-
targeted drugs with radiotherapy or chemoradiotherapy. Such approaches have the …

It is estimated that in 2008 1.4 million patients in North America will be diagnosed with a
nonskin form of cancer (www. cancer. org), of which seventy-five percent will receive …

As our understanding of the molecular pathways driving tumorigenesis improves and more
druggable targets are identified, we have witnessed a concomitant increase in the …

The addition of chemotherapeutic agents to ionizing radiation has improved survival in many
malignancies. Cure rates may be further improved by adding novel targeted agents to …

Over the past century, technologic advances have promoted the evolution of radiation
therapy into a precise treatment modality allowing for the maximal administration of dose to …

Recent advances in understanding the tumor's biology in line with a constantly growing
number of innovative technologies have prompted characterization of patients' individual …

Background: The efficacy of radiotherapy (RT) for cancer treatment is limited by normal
tissue toxicity and by the intrinsic or acquired radioresistance of many tumours. Therefore …