[HTML][HTML] The glymphatic system and meningeal lymphatics of the brain: new understanding of brain clearance

G Yankova, O Bogomyakova… - Reviews in the …, 2021 - degruyter.com
The glymphatic system and meningeal lymphatics have recently been characterized.
Glymphatic system is a glia-dependent system of perivascular channels, and it plays an …

Lymphatic system in central nervous system

JL Thomas, L Jacob, L Boisserand - Medecine Sciences: M/S, 2019 - europepmc.org
The considerable metabolic activity of the central nervous system (CNS) requires an efficient
system of tissue drainage and detoxification. The CNS is however devoid of lymphatic …

The meningeal lymphatic vessels and the glymphatic system: Potential therapeutic targets in neurological disorders

G Li, Y Cao, X Tang, J Huang, L Cai… - Journal of Cerebral …, 2022 - journals.sagepub.com
The recent discovery of the meningeal lymphatic vessels (mLVs) and glymphatic pathways
has challenged the long-lasting dogma that the central nervous system (CNS) lacks a …

[HTML][HTML] Understanding the functions and relationships of the glymphatic system and meningeal lymphatics

A Louveau, BA Plog, S Antila, K Alitalo… - The Journal of …, 2017 - Am Soc Clin Investig
Recent discoveries of the glymphatic system and of meningeal lymphatic vessels have
generated a lot of excitement, along with some degree of skepticism. Here, we summarize …

Lymphatic drainage system of the brain: a novel target for intervention of neurological diseases

BL Sun, L Wang, T Yang, J Sun, L Mao, M Yang… - Progress in …, 2018 - Elsevier
The belief that the vertebrate brain functions normally without classical lymphatic drainage
vessels has been held for many decades. On the contrary, new findings show that functional …

[HTML][HTML] The brain's glymphatic system: current controversies

H Mestre, Y Mori, M Nedergaard - Trends in neurosciences, 2020 - cell.com
The glymphatic concept along with the discovery of meningeal lymphatic vessels have, in
recent years, highlighted that fluid is directionally transported within the central nervous …

[HTML][HTML] Lymphatics in neurological disorders: a neuro-lympho-vascular component of multiple sclerosis and Alzheimer's disease?

A Louveau, S Da Mesquita, J Kipnis - Neuron, 2016 - cell.com
Lymphatic vasculature drains interstitial fluids, which contain the tissue's waste products,
and ensures immune surveillance of the tissues, allowing immune cell recirculation. Until …

[Retracted] Glymphatic System: Emerging Therapeutic Target for Neurological Diseases

X Xuan, G Zhou, C Chen, A Shao… - Oxidative Medicine …, 2022 - Wiley Online Library
The newly discovered glymphatic system acts as pseudolymphatic vessels subserving brain
waste clearance and is functionally dependent on astrocytic aquaporin‐4 channels. The …

Our current understanding of the lymphatics of the brain and spinal cord

G Dupont, C Schmidt, E Yilmaz, RJ Oskouian… - Clinical …, 2019 - Wiley Online Library
The lymphatic system, segregated from the blood vascular system, is an essential
anatomical route along which interstitial fluid, solutes, lipids, immune cells, and cellular …

[HTML][HTML] The lymphatic drainage systems in the brain: a novel target for ischemic stroke?

YJ Wang, YR Sun, YH Pei, HW Ma, YK Mu… - Neural regeneration …, 2023 - journals.lww.com
Recent studies have proposed three lymphatic drainage systems in the brain, that is, the
glymphatic system, the intramural periarterial drainage pathway, and meningeal lymphatic …