The glymphatic system is a recently discovered network unique to the central nervous
system that allows for dynamic exchange of interstitial fluid (ISF) and cerebrospinal fluid …

Normal physiologic function of organs requires a circulation of interstitial fluid to deliver
nutrients and clear cellular waste products. Lymphatic vessels serve as collectors of this fluid …

The comprehension of the glymphatic system, a postulated mechanism responsible for the
removal of interstitial solutes within the central nervous system (CNS), has witnessed …

The glymphatic concept along with the discovery of meningeal lymphatic vessels have, in
recent years, highlighted that fluid is directionally transported within the central nervous …

In recent years, the existence of a mass transport system in the brain via cerebrospinal fluid
(CSF) or interstitial fluid (ISF) has been suggested by many studies. The glymphatic system …

The central nervous system (CNS) is unique in being the only organ system lacking
lymphatic vessels to assist in the removal of interstitial metabolic waste products. Recent …

Derived from rodent studies, the glymphatic system was described in 2012 as a pathway
facilitating perivascular clearance of solutes from the brain interstitial fluid (ISF)[1]. The term …

After the introduction of the glymphatic system hypothesis, an increasing number of studies
on cerebrospinal fluid and interstitial fluid dynamics within the brain have been investigated …

The complex and dynamic system of fluid flow through the perivascular and interstitial
spaces of the CNS has new-found implications for neurological diseases. CSF movement …

The glymphatic system is a brain-wide perivascular pathway driven by aquaporin-4 on the
endfeet of astrocytes, which can deliver nutrients and active substances to the brain …