Malignant gliomas, the most common type of primary brain tumor, are a spectrum of tumors
of varying differentiation and malignancy grades. These tumors may arise from neural stem …

Introduction: Research into the pathogenesis, molecular signaling, and treatment of
glioblastoma multiforme (GBM) has traditionally been conducted using cell lines derived …

Glioblastoma (GBM) is the most invasive and deadliest brain cancer in adults. Its inherent
heterogeneity has been designated as the main cause of treatment failure. Thus, a deeper …

Glioblastoma (GBM) is one of the deadliest human cancers. Because of the extremely
unfavorable prognosis of GBM, it is important to develop more effective diagnostic and …

Glioblastoma multiforme (GBM) has been subdivided into two types based on clinical and
genetic findings: primary tumors, which arise de novo, and secondary tumors, which …

Glioblastoma (GBM) is the most common primary malignant brain tumour in adults. Despite
the combination of novel therapeutical approaches, it remains a deadly malignancy with an …

Abstract The World Health Organization (WHO) classification system for glial tumors
provides guidance as to the predicted course of the disease and choice of treatment …

As the molecular events responsible for astrocytoma formation and progression are being
clarified, it is becoming possible to correlate these alterations with the specific …

Glioblastoma (GB) is the most frequent and aggressive primary tumor of the central nervous
system. Prognosis remains poor despite ongoing progress. In cases where the gadolinium …

Glioblastoma is a highly malignant brain tumor that relentlessly defies therapy. Efforts over
the past decade have begun to tease out the biochemical details that lead to its aggressive …