Over the past several years, significant technological and biological progress has been
made in radiation oncology with focus on the development of new treatment schemes to …

Use of radiation for cancer therapy began shortly after the discovery of X-rays in 1895.
Technological advances over the ensuing 120 years have enabled the development of …

There is a growing appreciation of the potential value of combining novel molecularly-
targeted drugs with radiotherapy or chemoradiotherapy. Such approaches have the …

The practice of radiation oncology is currently primarily based on precise technical delivery
of highly conformal, image-guided radiation treatments. The precision medicine revolution …

Radiation therapy is commonly used in the curative treatment of cancer. Despite recent
progress in the techniques of radiation delivery and treatment, local recurrence after …

The combination of molecular-targeted agents with irradiation is a highly promising avenue
for cancer research and patient care. Molecular-targeted agents are in themselves not …

There is an urgent need to improve reproducibility and translatability of preclinical data to
fully exploit opportunities for molecular therapeutics involving radiation and …

It is estimated that in 2008 1.4 million patients in North America will be diagnosed with a
nonskin form of cancer (www. cancer. org), of which seventy-five percent will receive …

External beam radiotherapy is indicated in approximately 50-60% of human cancer patients.
The prescribed dose of ionizing radiation that can be delivered to a tumor is determined by …

Molecular Targeted Radiosensitizers: Opportunities and Challenges provides the reader
with a comprehensive review of key pre-clinical research components required to identify …