Integrative radiogenomic profiling of squamous cell lung cancer
ME Abazeed, DJ Adams, KE Hurov, P Tamayo… - Cancer research, 2013 - AACR
Radiotherapy is one of the mainstays of anticancer treatment, but the relationship between
the radiosensitivity of cancer cells and their genomic characteristics is still not well defined …
the radiosensitivity of cancer cells and their genomic characteristics is still not well defined …
The clinical development of molecularly targeted agents in combination with radiation therapy: a pharmaceutical perspective
OU Ataman, SJ Sambrook, C Wilks, A Lloyd… - International Journal of …, 2012 - Elsevier
This paper explores historical and current roles of pharmaceutical industry sponsorship of
clinical trials testing radiation therapy combinations with molecularly targeted agents and …
clinical trials testing radiation therapy combinations with molecularly targeted agents and …
Radiogenomics predicting tumor responses to radiotherapy in lung cancer
AK Das, MH Bell, CS Nirodi, MD Story… - Seminars in radiation …, 2010 - Elsevier
The recently developed ability to interrogate genome-wide data arrays has provided
invaluable insights into the molecular pathogenesis of lung cancer. These data have also …
invaluable insights into the molecular pathogenesis of lung cancer. These data have also …
Radiosensitising agents for the radiotherapy of cancer: novel molecularly targeted approaches
F Dumont, A Altmeyer, P Bischoff - Expert opinion on therapeutic …, 2009 - Taylor & Francis
Background: The efficacy of radiotherapy (RT) for cancer treatment is limited by normal
tissue toxicity and by the intrinsic or acquired radioresistance of many tumours. Therefore …
tissue toxicity and by the intrinsic or acquired radioresistance of many tumours. Therefore …
Increasing the therapeutic ratio of radiotherapy
PJ Tofilon, K Camphausen - 2017 - Springer
Cancer Drug Discovery and Development, the Springer series headed by Beverly A.
Teicher, is the definitive book series in cancer research and oncology. Volumes cover the …
Teicher, is the definitive book series in cancer research and oncology. Volumes cover the …
[PDF][PDF] Combining radiation and molecular targeting in cancer therapy
K Camphausen, PJ Tofilon - Cancer biology & therapy, 2004 - Taylor & Francis
Radiotherapy continues to remain a major treatment modality for solid tumors. However,
advances in fundamental radiobiology suggest that improvements in tumor control can be …
advances in fundamental radiobiology suggest that improvements in tumor control can be …
Translation of precision medicine research into biomarker-informed care in radiation oncology
JA Scarborough, JG Scott - Seminars in radiation oncology, 2022 - Elsevier
The reach of personalized medicine in radiation oncology has expanded greatly over the
past few decades as technical precision has improved the delivery of radiation to each …
past few decades as technical precision has improved the delivery of radiation to each …
[HTML][HTML] Model selection for the preclinical development of new drug–radiotherapy combinations
Radiotherapy plays an essential role in the treatment of more than half of all patients with
cancer. In recent decades, advances in devices that deliver radiation and the development …
cancer. In recent decades, advances in devices that deliver radiation and the development …
Moving beyond the standard of care: accelerate testing of radiation-drug combinations
SH Lin, H Willers, S Krishnan, JN Sarkaria… - International Journal of …, 2021 - Elsevier
Radiation therapy is a major treatment modality used in> 60% of cancer patients as
definitive local treatment for inoperable locoregionally confined tumors and as palliative …
definitive local treatment for inoperable locoregionally confined tumors and as palliative …