OBJECTIVES The primary objective of this retrospective study was to determine if
implementation of vancomycin monitoring criteria could reduce the number of serum …

The objectives of this study were to estimate the prevalence of low or excessive vancomycin
dosing after initiation of treatment in pediatric patients and to determine the factors that are …

Background Because of concerns regarding increasing microbial resistance to vancomycin,
adult treatment guidelines recommend higher trough concentrations based on the type of …

Background Methicillin-resistant Staphylococcus aureus (MRSA) infections among children
are escalating annually. Vancomycin stands as the frontline therapeutic agent against …

Background: Vancomycin treatment failures in adults with methicillin-resistant
Staphylococcus aureus bacteremia are well documented despite established therapeutic …

OBJECTIVES Appropriate antimicrobial dosing maximizes therapeutic benefit while
minimizing development of antimicrobial resistance. Common pediatric references …

Background: Vancomycin is widely used to treat infections caused by methicillin-resistant
Staphylococcus aureus. Data for dosing and monitoring of this drug in pediatric patients are …

Background Pediatric studies and anecdotal experience suggest that current empiric
vancomycin dosing does not reach serum trough concentration targets of at least 10 mg/L for …

Monitoring of vancomycin trough concentrations is recommended for pediatric patients in the
product label and by several professional societies. However, among a network of …

Aim Vancomycin guidelines for therapeutic drug monitoring (TDM) aim to maximise efficacy
while minimising toxicity and resistance. Vancomycin is effective against Staphylococcus …