It is estimated that in 2008 1.4 million patients in North America will be diagnosed with a
nonskin form of cancer (www. cancer. org), of which seventy-five percent will receive …

Studies aimed at understanding the mechanisms responsible for regulating cellular
response to ionizing radiation have resulted in the identification of a wide variety of …

Chemoradiation, either alone or in combination with surgery or induction chemotherapy, is
the current standard of care for most locally advanced solid tumors. Though chemoradiation …

The first annual workshop for preclinical and clinical development of radiosensitizers took
place at the National Cancer Institute on August 8–9, 2012. Radiotherapy is one of the most …

Radiation therapy is a highly effective cancer treatment modality, and extensive
investigations have been undertaken over the years to augment its efficacy in the clinic. This …

Background: The efficacy of radiotherapy (RT) for cancer treatment is limited by normal
tissue toxicity and by the intrinsic or acquired radioresistance of many tumours. Therefore …

Radiotherapy continues to remain a major treatment modality for solid tumors. However,
advances in fundamental radiobiology suggest that improvements in tumor control can be …

There is a growing appreciation of the potential value of combining novel molecularly-
targeted drugs with radiotherapy or chemoradiotherapy. Such approaches have the …

The development of molecular targeted drugs with radiation and chemotherapy is critically
important for improving the outcomes of patients with hard-to-treat, potentially curable …

The last two decades have seen technological developments that have led to more accurate
delivery of radiation therapy (RT), which has resulted in clinical gains in many solid tumors …