There is a growing appreciation of the potential value of combining novel molecularly-
targeted drugs with radiotherapy or chemoradiotherapy. Such approaches have the …

The combination of chemotherapy and radiation has led to clinical breakthroughs in several
disease sites, and current work continues to define optimum combinations of proven …

The addition of chemotherapeutic agents to ionizing radiation has improved survival in many
malignancies. Cure rates may be further improved by adding novel targeted agents to …

Radiation therapy is a highly effective cancer treatment modality, and extensive
investigations have been undertaken over the years to augment its efficacy in the clinic. This …

The first annual workshop for preclinical and clinical development of radiosensitizers took
place at the National Cancer Institute on August 8–9, 2012. Radiotherapy is one of the most …

The combination of molecular-targeted agents with irradiation is a highly promising avenue
for cancer research and patient care. Molecular-targeted agents are in themselves not …

The ideal radiation sensitizer would reach the tumor in adequate concentrations and act
selectively in the tumor compared with normal tissue. It would have predictable …

Combining chemotherapy with radiotherapy has resulted in significant clinical improvements
in many different tumour types. However, the non-specific mechanisms by which these drugs …

It is estimated that in 2008 1.4 million patients in North America will be diagnosed with a
nonskin form of cancer (www. cancer. org), of which seventy-five percent will receive …

Background: Radiotherapy is utilised for the treatment of∼ 50% of patients with solid
tumours, but its efficacy is limited by normal tissue toxicity and by the intrinsic or acquired …