634 Achieving therapeutic vancomycin levels in neonates-a quality improvement initiative

A Garg, M Vidouris, PK Loganathan - 2022 - adc.bmj.com
Aims Background Vancomycin is a commonly used antibiotic in the neonatal unit. Its efficacy
correlates directly with the duration of bacterial exposure at therapeutic levels. In our unit, we …

Achievement of therapeutic vancomycin exposure with continuous infusion in critically ill children

M Genuini, M Oualha, N Bouazza… - Pediatric Critical Care …, 2018 - journals.lww.com
Objective: Describe and assess a continuous infusion dosing scheme of vancomycin
therapy in critically ill children. Design: Retrospective single-center study, January to June …

Clinical Application Value of Pharmacokinetic Parameters of Vancomycin in Children Treated in the Pediatric Intensive Care Unit

Y Fu, C Liu - Improving Efficacy and Safety of Drugs in Pediatric …, 2022 - books.google.com
Objective: To explore the efficacy and safety of vancomycin as measured by
pharmacokinetic/pharmacodynamic parameters in children with severe infection in the …

Evaluation of vancomycin dosing and monitoring in adult medicine patients

S Devabhakthuni, JP Gonzales, AL Tata… - Hospital …, 2012 - journals.sagepub.com
Purpose To assess the clinical impact of a vancomycin dosing protocol and monitoring tool
on initial dose, dosing interval, and trough concentrations in adult medicine patients …

AUC‐guided vancomycin dosing in adolescent patients with suspected sepsis

S Lanke, T Yu, JE Rower, AH Balch… - The Journal of …, 2017 - Wiley Online Library
Vancomycin is a first‐line treatment for β‐lactam‐resistant Gram‐positive bacterial
infections. Understanding the pharmacokinetic (PK) and pharmacodynamic (PD) …

Implementation of the systems approach to improve a pharmacist-managed vancomycin dosing service

DJ Gagnon, R Roberts, L Sylvia - American Journal of Health …, 2014 - academic.oup.com
Purpose Quality improvements achieved by applying the systems approach to assess the
clinical effectiveness, operational efficiency, and financial feasibility of a pharmacist …

Role of fluid status markers as risk factors for suboptimal vancomycin concentration during continuous infusion in neonates: an observational study

VL Cousin, Q Laudouar, N Le Sache… - European Journal of …, 2022 - Springer
Vancomycin is widely used in neonatal sepsis but proportion of newborn reaching
recommended concentration is variable. Fluid status impact on vancomycin level remains …

Pharmacokinetic comparison of nomogram-based and individualized vancomycin regimens in neonates

T Crumby, E Rinehart, MC Carby… - American Journal of …, 2009 - academic.oup.com
Purpose. This study compared steady-state concentrations achieved with a dosing strategy
using first-dose kinetics to individualize vancomycin regimens with the steady-state …

Vancomycin therapeutic drug monitoring in paediatrics

J Patel, CJ Lucas, J Ryan, M Jenkins… - Journal of Paediatrics …, 2020 - Wiley Online Library
Aim Vancomycin guidelines for therapeutic drug monitoring (TDM) aim to maximise efficacy
while minimising toxicity and resistance. Vancomycin is effective against Staphylococcus …

Vancomycin therapeutic drug monitoring in children: new recommendations, similar challenges

JC McNeil, SL Kaplan - The Journal of Pediatric …, 2020 - meridian.allenpress.com
The American Society of Health-System Pharmacists, the Infectious Diseases Society of
America, the Pediatric Infectious Diseases Society, and the Society of Infectious Diseases …