Mesenchymal stem cell-based treatment in autoimmune liver diseases: underlying roles, advantages and challenges

C He, Y Yang, K Zheng, Y Chen, S Liu… - … in Chronic Disease, 2021 - journals.sagepub.com
Autoimmune liver disease (AILD) is a series of chronic liver diseases with abnormal immune
responses, including autoimmune hepatitis (AIH), primary biliary cholangitis (PBC), and …

[HTML][HTML] Current understanding of mesenchymal stem cells in liver diseases

MC Wu, QH Meng - World journal of stem cells, 2021 - ncbi.nlm.nih.gov
Liver diseases caused by various factors have become a significant threat to public health
worldwide. Liver transplantation has been considered as the only effective treatment for end …

The application of mesenchymal stem cells in the treatment of liver diseases: mechanism, efficacy, and safety issues

Y Yang, Y Zhao, L Zhang, F Zhang, L Li - Frontiers in Medicine, 2021 - frontiersin.org
Mesenchymal stem cell (MSC) transplantation is a novel treatment for liver diseases due to
the roles of MSCs in regeneration, fibrosis inhibition and immune regulation. However, the …

Mesenchymal stem cells-based therapy in liver diseases

HT Han, WL Jin, X Li - Molecular Biomedicine, 2022 - Springer
Multiple immune cells and their products in the liver together form a complex and unique
immune microenvironment, and preclinical models have demonstrated the importance of …

Liver disease and cell therapy: advances made and remaining challenges

S Khan, S Mahgoub, N Fallatah, PF Lalor… - Stem Cells, 2023 - academic.oup.com
The limited availability of organs for liver transplantation, the ultimate curative treatment for
end stage liver disease, has resulted in a growing and unmet need for alternative therapies …

Advance of Mesenchymal Stem Cells in Chronic End‐Stage Liver Disease Control

Y Gao, X Yin, X Ren - Stem Cells International, 2022 - Wiley Online Library
The chronic liver diseases will slowly develop into liver fibrosis, cirrhosis, and even liver
cancer if no proper control is performed with high efficiency. Up to now, the most effective …

Mesenchymal stem cell therapy for liver disease: full of chances and challenges

X Yang, Y Meng, Z Han, F Ye, L Wei, C Zong - Cell & bioscience, 2020 - Springer
Liver disease is a major health problem that endangers human health worldwide. Currently,
whole organ allograft transplantation is the gold standard for the treatment of end-stage liver …

Multiple dimensions of using mesenchymal stem cells for treating liver diseases: From bench to beside

L Chen, N Zhang, Y Huang, Q Zhang, Y Fang… - Stem Cell Reviews and …, 2023 - Springer
Liver diseases impose a huge burden worldwide. Although hepatocyte transplantation has
long been considered as a potential strategy for treating liver diseases, its clinical …

[HTML][HTML] Mesenchymal stem cell therapy for liver fibrosis/cirrhosis

Y Cao, C Ji, L Lu - Annals of translational medicine, 2020 - ncbi.nlm.nih.gov
Liver fibrosis represents a common outcome of most chronic liver diseases. Advanced
fibrosis leads to cirrhosis for which no effective treatment is available except liver …

Advancements in mesenchymal stem cell therapy for liver cirrhosis: Unveiling origins, treatment mechanisms, and current research frontiers

Z Wang, L Yao, X Hu, M Yuan, P Chen, P Liu, Q Zhang… - Tissue and Cell, 2023 - Elsevier
Chronic liver disease inevitably progresses to liver cirrhosis, significantly compromising
patients' overall survival and quality of life. However, a glimmer of hope emerges with the …