JAK2 disease-risk variants are gain of function and JAK signaling threshold determines innate receptor-induced proinflammatory cytokine secretion in macrophages

M Hedl, DD Proctor, C Abraham - The Journal of Immunology, 2016 - journals.aai.org
JAK2 genetic variants are associated with inflammatory bowel disease (IBD) and JAK
inhibitors are being evaluated for therapy targeting immune-mediated diseases, including …

JAK2 Disease-Risk Variants Are Gain of Function and JAK Signaling Threshold Determines Innate Receptor-Induced Proinflammatory Cytokine Secretion in …

M Hedl, DD Proctor, C Abraham - Journal of immunology …, 2016 - pubmed.ncbi.nlm.nih.gov
JAK2 genetic variants are associated with inflammatory bowel disease (IBD) and JAK
inhibitors are being evaluated for therapy targeting immune-mediated diseases, including …

[HTML][HTML] JAK2 Disease-Risk Variants are Gain of Function and JAK Signaling Threshold Determines Innate Receptor-Induced Proinflammatory Cytokine Secretion in …

M Hedl, DD Proctor, C Abraham - Journal of immunology …, 2016 - ncbi.nlm.nih.gov
JAK2 genetic variants are associated with inflammatory bowel disease (IBD) and JAK
inhibitors are being evaluated for therapy targeting immune-mediated diseases, including …

JAK2 Disease-Risk Variants Are Gain of Function and JAK Signaling Threshold Determines Innate Receptor-Induced Proinflammatory Cytokine Secretion in …

M Hedl, DD Proctor, C Abraham - Journal of Immunology (Baltimore …, 2016 - europepmc.org
JAK2 genetic variants are associated with inflammatory bowel disease (IBD) and JAK
inhibitors are being evaluated for therapy targeting immune-mediated diseases, including …