Integrated strategy of network pharmacology, molecular docking, HPLC-DAD and mice model for exploring active ingredients and pharmacological mechanisms of …

Y Jiang, M Zhong, H Zhan, X Tao, Y Zhang… - Journal of …, 2022 - Elsevier
Abstract Ethnopharmacological relevance Penthorum chinense Pursh (PCP, Saxifragaceae)
is an edible plant and frequently-used Chinese herbal medicine, and is commonly used as …

Polyphenol-enriched Penthorum chinense Pursh ameliorates alcohol-related liver injury through Ras/Raf/MEK/ERK pathway: Integrating network pharmacology and …

R Li, D Wu, J Hu, Y Ma, Y Ba, L Zou, Y Hu - Journal of Ethnopharmacology, 2024 - Elsevier
Abstract Ethnopharmacological relevance Penthorum chinense Pursh (PCP) has
acknowledged as an edible herbal medicinal plant for the prevention and treatment of …

Liver injury protection of Artemisia stechmanniana besser through PI3K/AKT pathway

CB Tian, ML Qin, YL Qian, SS Qin, ZQ Shi… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Artemisia stechmanniana Besser, one of the most
prevalent botanical medicines in Chinese, has been traditionally used for hepatitis …

Chrysanthemi Flos extract alleviated acetaminophen-induced rat liver injury via inhibiting oxidative stress and apoptosis based on network pharmacology analysis

Y Zhou, C Wang, J Kou, M Wang, X Rong… - Pharmaceutical …, 2021 - Taylor & Francis
Context Acetaminophen (APAP) overdose is the leading cause of drug-induced liver injury.
Bianliang ziyu, a variety of Chrysanthemum morifolium Ramat.(Asteraceae), has potential …

Bio-assay guided identification of hepatoprotective polyphenols from Penthorum chinense Pursh on t-BHP induced oxidative stress injured L02 cells

A Wang, S Wang, Y Jiang, M Chen, Y Wang, L Lin - Food & Function, 2016 - pubs.rsc.org
Penthorum chinense Pursh (Ganhuangcao in Chinese) is traditionally used for liver
protection and treatment of liver diseases, including hepatitis B, hepatitis C and alcoholic …

[HTML][HTML] Hepatoprotective effect of Citrus aurantium L. against APAP-induced liver injury by regulating liver lipid metabolism and apoptosis

Y Shu, D He, W Li, M Wang, S Zhao, L Liu… - … journal of biological …, 2020 - ncbi.nlm.nih.gov
Acetaminophen (APAP) refers to a medication used to manage pain and fever symptoms,
but it always causes liver injury when overdosed. Zhishi, dried young fruit of Citrus …

Evaluating the Potential of Glycyrrhiza uralensis (Licorice) in Treating Alcoholic Liver Injury: A Network Pharmacology and Molecular Docking Analysis Approach

L Zhu, S Xie, Z Geng, X Yang, Q Zhang - Processes, 2022 - mdpi.com
Glycyrrhiza uralensis is used to treat alcoholic liver injury in China; however, its
pharmacological mechanism remains to be clarified. Here, the potential of G. uralensis for …

[HTML][HTML] Preliminary study on the effective site and mechanism of action of Meconopsis quintuplinervia Regel in alleviating acute alcoholic liver injury in mice

J Chen, Q Zhang, R Wang, Y Yang, Y Wang… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance Meconopsis quintuplinervia Regel (MQR)
belongs to the opium poppy tree plant species, and it has heat purging, detoxification …

Phytochemical composition, isolation and hepatoprotective activity of active fraction from Veronica ciliata against acetaminophen-induced acute liver injury via p62 …

Q Lu, S Tan, W Gu, F Li, W Hua, S Zhang… - Journal of …, 2019 - Elsevier
Abstract Ethnopharmacological relevance Veronica ciliata Fisch, a traditional Tibetan
medicine, used to cure hepatitis and existed in lots of Tibetan medicine prescriptions owing …

Paeonia lactiflora Pall. ameliorates acetaminophen-induced oxidative stress and apoptosis via inhibiting the PKC-ERK pathway

Y Li, X Deng, Q Hu, Y Chen, W Zhang, X Qin… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Paeonia lactiflora Pall.(PLP), a traditional
Chinese medicine, is recognized for its antioxidative and anti-apoptotic properties. Despite …