[HTML][HTML] TIPE2 functions as a metastasis suppressor via negatively regulating β-catenin through activating GSK3β in gastric cancer

J Wu, H Zhang, C Xu, H Xu… - International …, 2016 - spandidos-publications.com
Tumor necrosis factor (TNF)-α-induced protein 8-like 2 (TNFAIP8L2, TIPE2) is a novel anti-
inflammatory factor involved in maintaining immune homeostasis. Accumulating evidence …

DUSP8/TAK1 signaling mediates neuropathic pain through regulating neuroinflammation and neuron death in a spinal nerve ligation (SNL) rat model

C Liao, H Zhou, H Chen, G Cheng, S Li, F Ma… - International …, 2022 - Elsevier
Nerve injury-induced neuropathic pain is a type of chronic pain associated with
neuroinflammatory response and neuronal death; however the underlying molecular …

[HTML][HTML] TNF-α-induced protein 8-like 2 negatively regulates the immune function of dendritic cells by suppressing autophagy via the TAK1/JNK pathway in septic mice

SQ Liu, C Ren, RQ Yao, Y Wu, YY Luan, N Dong… - Cell Death & …, 2021 - nature.com
Tumor necrosis factor (TNF)-α-induced protein 8-like 2 (TIPE2) is a newly discovered
negative immunoregulatory protein that is involved in various cellular immune responses to …

[HTML][HTML] TIPE3 promotes non-small cell lung cancer progression via the protein kinase B/extracellular signal-regulated kinase 1/2-glycogen synthase kinase 3β-β …

Q Li, D Yu, Z Yu, Q Gao, R Chen, L Zhou… - Translational Lung …, 2021 - ncbi.nlm.nih.gov
Background Tumor necrosis factor-α-induced protein 8-like 3 (TNFAIP8L3, also called
TIPE3) has been shown to activate PI3K-AKT and MEK-ERK pathways. However, the roles …

[HTML][HTML] TIPE2 suppresses angiogenesis and non-small cell lung cancer (NSCLC) invasiveness via inhibiting Rac1 activation and VEGF expression

Z Li, C Guo, X Liu, C Zhou, F Zhu, X Wang, Q Wang… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Non-small cell lung cancer (NSCLC) is one of the leading causes of all cancer-related
deaths worldwide. Despite extensive efforts to improve the diagnosis and treatment of this …

[HTML][HTML] In silico analysis of tumor necrosis factor α-induced protein 8-like-1 (TIPE1) protein

P Shen, H Zhang, Z Su, S Wang, H Xu - PloS one, 2015 - journals.plos.org
Tumor necrosis factor α-induced protein 8 (TNFAIP8)-like protein 1 (TIPE1) was a member of
TNFAIP8 family. Previous studies have shown that TIPE1 could induce apoptosis in …

A novel inflammatory regulator TIPE2 inhibits TLR4-mediated development of colon cancer via caspase-8

XM Li, JR Su, SP Yan, ZL Cheng, TT Yang… - Cancer …, 2014 - content.iospress.com
Aims: TIPE2 is a novel inflammation regulator, and the role of TIPE2 in colitis-induced colon
cancer is not clear. The aim of this study was to test whether TIPE2 inhibits TLR4 pathway in …

Tissue-specific expression of TIPE2 provides insights into its function

G Zhang, C Hao, Y Lou, W Xi, X Wang, Y Wang… - Molecular …, 2010 - Elsevier
Tumor necrosis factor-alpha-induced protein-8 like-2 (TNFAIP8L2, TIPE2) is a newly
discovered negative regulator of innate immunity and cellular immunity. TIPE2 deficiency in …

TRAF6 contributes to CFA-induced spinal microglial activation and chronic inflammatory pain in mice

Y Lu, DL Cao, LJ Ma, YJ Gao - Cellular and Molecular Neurobiology, 2022 - Springer
Tumor necrosis factor receptor-associated factor 6 (TRAF6) has been reported to be
expressed in spinal astrocytes and is involved in neuropathic pain. In this study, we …

Stress‐induced phosphoprotein 1 restrains spinal cord ischaemia‐reperfusion injury by modulating NF‐κB signalling

H Jin, X Ge, Z Huan, H Yao, C Xu… - Journal of Cellular and …, 2021 - Wiley Online Library
Spinal cord injury (SCI), a major cause of disability, causes high global disease and
economic burdens. Stress‐induced phosphoprotein 1 (STIP1) has been identified to be …