[HTML][HTML] Challenges to the clinical application of pluripotent stem cells: towards genomic and functional stability

X Fu, Y Xu - Genome medicine, 2012 - Springer
Human embryonic stem cells (hESCs) can undergo unlimited self-renewal and are
pluripotent, retaining the ability to differentiate into all cell types in the body. As a renewable …

Stem Cells without Embryos-Solving Dilemmas for Human Rights

JA Burger - Hum. Rts., 2007 - HeinOnline
Recent stem cell research results have raised hope that the heady promise of stem cell
technology will soon be realized. Two independent teams of researchers in November 2007 …

[PDF][PDF] Should the US Government Fund Human Embryonic Stem Cell Research?

J Liu - 2023 - ajosr.org
Human embryonic stem (ES) cells isolated from human embryos are pluripotent and they
have the remarkable ability to differentiate into all different cell types in the human body, thus …

Reprogramming human somatic cells into induced pluripotent stem cells (iPSCs) using retroviral vector with GFP

KY Kim, E Hysolli, IH Park - JoVE (Journal of Visualized Experiments), 2012 - jove.com
Human embryonic stem cells (hESCs) are pluripotent and an invaluable cellular sources for
in vitro disease modeling and regenerative medicine1. It has been previously shown that …

[HTML][HTML] Human endogenous retrovirus K (HML-2) RNA and protein expression is a marker for human embryonic and induced pluripotent stem cells

NV Fuchs, S Loewer, GQ Daley, Z Izsvák, J Löwer… - Retrovirology, 2013 - Springer
Background Malignant human embryonal carcinoma cells (ECCs) rely on similar
transcriptional networks as non-malignant embryonic stem cells (ESCs) to control …

Intellectual property of human pluripotent stem cells

ML Rohrbaugh - Human Embryonic Stem Cells, 2009 - Springer
Intellectual property arose as a principle implementation issue after President Bush
announced his decision on August 9, 2001 to permit federal funding for qualified human …

[HTML][HTML] Safety Assessment of Reprogrammed Cells Prior to Clinical Applications: Potential Approaches to Eliminate Teratoma Formation

JC Polanco, AL Laslett - Pluripotent Stem Cells, 2013 - intechopen.com
Human pluripotent stem cells (hPSC) include human embryonic stem cells (hESC) and hu‐
man induced pluripotent stem cells (hIPSC). Due to their inherent ability to self-renew in …

[引用][C] Induced reprogramming of human somatic cells into pluripotency: a new way how to generate pluripotent stem cells

G Durcova-Hills - Differentiation, 2008 - Elsevier
ES cells are remarkable cells. They can self-renew and maintain pluripotency indefinitely or
can differentiate into any cellular types in the body. Therefore human ES (hES) cells provide …

[HTML][HTML] Genomic integrity of human induced pluripotent stem cells: Reprogramming, differentiation and applications

C Steichen, Z Hannoun, E Luce, T Hauet… - World journal of stem …, 2019 - ncbi.nlm.nih.gov
Ten years after the initial generation of induced pluripotent stem cells (hiPSCs) from human
tissues, their potential is no longer questioned, with over 15000 publications listed on …

Identification of unsafe human induced pluripotent stem cell lines using a robust surrogate assay for pluripotency

JC Polanco, MSH Ho, B Wang, Q Zhou… - Stem Cells, 2013 - academic.oup.com
Human induced pluripotent stem cells (hiPSC) have the potential to generate healthy cells
and tissues for the study and medical treatment of a large number of diseases. The utility of …