Human chromosome fragments and human artificial chromosomes (HAC) represent feasible
gene delivery vectors via microcell-mediated chromosome transfer. Strategies to construct …

Recent work from our group and others has argued that human induced pluripotent stem
cells (hiPSCs) generated by the introduction of four viruses bearing reprogramming factors …

Human induced pluripotent stem cells can be obtained from somatic cells, and their
derivation does not require destruction of embryos, thus avoiding ethical problems arising …

Abstract In 2006, Shinya Yamanaka generated induced pluripotent stem cells (iPSCs),
which has been the major scientific event of the decade that caught the eye of many …

Human induced pluripotent stem cells (hiPSCs) and hiPSCs-derived cells have the potential
to revolutionize regenerative and precision medicine. Genetically reprograming somatic …

The generation of human induced pluripotent stem cells (hiPSCs) opens a new avenue in
regenerative medicine. However, transplantation of hiPSC-derived cells carries a risk of …

Genetic engineering of induced pluripotent stem cells (iPSCs) holds great promise for gene
and cell therapy as well as drug discovery. However, there are potential concerns regarding …

Human induced pluripotent stem cells (hiPSCs) can be genetically reprogrammed to an
embryonic stem cell-like state and can provide promising medical applications, such as …

The ability to derive and stably maintain ground-state human pluripotent stem cells (hPSCs)
that resemble the cells seen in vivo in the inner cell mass has the potential to be an …

Although many techniques can be used to generate multitype-induced pluripotent stem (iPS)
cells from multitype seed cells, improving the efficiency and shortening the period of cell …