Rho family GTPases as key regulators for neuronal network formation
M Negishi, H Katoh - The journal of biochemistry, 2002 - academic.oup.com
Rho family GTPases act as transducers of signals from extracellular stimuli to the
cytoskeleton and gene expression. Their actions are temporal and spatial determinants for …
cytoskeleton and gene expression. Their actions are temporal and spatial determinants for …
RhoB in cancer suppression
M Huang, GC Prendergast - Histology and histopathology, 2006 - digitum.um.es
RhoB is a mainly endosomal small GTPase that regulates actin organization and vesicle
trafficking. Expression of RhoB is elevated rapidly by many stimuli, including growth factors …
trafficking. Expression of RhoB is elevated rapidly by many stimuli, including growth factors …
Rho GTPases and signaling networks
L Van Aelst, C D'Souza-Schorey - Genes & development, 1997 - genesdev.cshlp.org
The Rho GTPases form a subgroup of the Ras superfamily of 20-to 30-kD GTP-binding
proteins that have been shown to regulate a wide spectrum of cellular functions. These …
proteins that have been shown to regulate a wide spectrum of cellular functions. These …
[HTML][HTML] A current overview of RhoA, RhoB, and RhoC functions in vascular biology and pathology
R Eckenstaler, M Hauke, RA Benndorf - Biochemical Pharmacology, 2022 - Elsevier
The Rho subfamily members of Rho GTPases, RhoA, RhoB, and RhoC, are key regulators
of signal transduction in a variety of cellular processes, including regulation of actomyosin …
of signal transduction in a variety of cellular processes, including regulation of actomyosin …
RhoA signaling in cardiomyocytes protects against stress-induced heart failure but facilitates cardiac fibrosis
J Lauriol, K Keith, F Jaffré, A Couvillon, A Saci… - Science …, 2014 - science.org
The Ras-related guanosine triphosphatase RhoA mediates pathological cardiac
hypertrophy, but also promotes cell survival and is cardioprotective after …
hypertrophy, but also promotes cell survival and is cardioprotective after …
Rho GTPases in intellectual disability: from genetics to therapeutic opportunities
V Zamboni, R Jones, A Umbach, A Ammoni… - International Journal of …, 2018 - mdpi.com
Rho-class small GTPases are implicated in basic cellular processes at nearly all brain
developmental steps, from neurogenesis and migration to axon guidance and synaptic …
developmental steps, from neurogenesis and migration to axon guidance and synaptic …
Signaling through Rho GTPase pathway as viable drug target
Signaling through the Rho family of small GTPases has been increasingly investigated for
their involvement in a wide variety of diseases such as cardiovascular, pulmonary, and …
their involvement in a wide variety of diseases such as cardiovascular, pulmonary, and …
Survival of developing motor neurons mediated by Rho GTPase signaling pathway through Rho-kinase
K Kobayashi, M Takahashi, N Matsushita… - Journal of …, 2004 - Soc Neuroscience
A variety of neurons generated during embryonic development survive or undergo
programmed cell death (PCD) at later developmental stages. Survival or death of …
programmed cell death (PCD) at later developmental stages. Survival or death of …
Rac1 GTPase: a “Rac” of all trades
EE Bosco, JC Mulloy, Y Zheng - Cellular and molecular life sciences, 2009 - Springer
Rac1, a member of the Rho family of GTPases, is an intracellular transducer known to
regulate multiple signaling pathways that control cytoskeleton organization, transcription …
regulate multiple signaling pathways that control cytoskeleton organization, transcription …
Signaling to rho GTPases
L Kjøller, A Hall - Experimental cell research, 1999 - Elsevier
Rho GTPases regulate many important processes in all eukaryotic cells, including the
organization of the actin cytoskeleton, gene transcription, cell cycle progression, and …
organization of the actin cytoskeleton, gene transcription, cell cycle progression, and …