Brain-derived neurotrophic factor (BDNF), in addition to its neurotrophic action, also
possesses antioxidant activities. However, the underlying mechanisms remain to be fully …

In addition to its well-established neurotrophic action, brain-derived neurotrophic factor
(BDNF) also possesses other neuroprotective effects including anti-apoptosis, anti …

OBJECTIVE: Oxidative injury is an essential part of the pathological changes of cerebral
ischemia-reperfusion. Sestrin2 (Sesn2), a conserved antioxidant protein, is activated under …

Sestrin2 (SESN2) is stress-inducible protein that confers cytoprotective effects against
various noxious stimuli. Accumulating evidence has documented that SESN2 has potent anti …

In current study, we tested the hypothesis that c-Jun-dependent sulfiredoxin expression
mediates protective effects of brain-derived neurotrophic factor (BDNF) against neurotoxicity …

Abstract Sestrin2 (Sesn2) exerts neuroprotective properties in some neurodegenerative
diseases. However, the role of Sesn2 in stroke is unclear. The AMP-activated protein …

Sinomenine (SN), a purified alkaloid from Chinese herb Sinomenium acutum that was used
preferentially in the treatment of rheumatoid diseases, has exerted neuroprotective effects …

Abstract Sestrin1 (Sesn1) acts as a stress-inducible protein that performs a remarkable
cytoprotective function upon diverse cellular stresses. However, whether Sesn1 exerts a …

Brain‐derived neurotrophic factor (BDNF) stimulates dendrite outgrowth and synaptic
plasticity by activating downstream protein kinase A (PKA) signaling. Recently, BDNF has …

Oxidative stress-induced neuronal cell damage is a crucial factor in the pathogenesis of
mitochondria-associated neurological diseases. Therefore, elimination of overproduction of …