Nuclear factor-kappaB-dependent sestrin2 induction mediates the antioxidant effects of BDNF against mitochondrial inhibition in rat cortical neurons
CL Wu, SD Chen, JH Yin, CS Hwang, DI Yang - Molecular Neurobiology, 2016 - Springer
Brain-derived neurotrophic factor (BDNF), in addition to its neurotrophic action, also
possesses antioxidant activities. However, the underlying mechanisms remain to be fully …
possesses antioxidant activities. However, the underlying mechanisms remain to be fully …
More insight into BDNF against neurodegeneration: anti-apoptosis, anti-oxidation, and suppression of autophagy
SD Chen, CL Wu, WC Hwang, DI Yang - International journal of molecular …, 2017 - mdpi.com
In addition to its well-established neurotrophic action, brain-derived neurotrophic factor
(BDNF) also possesses other neuroprotective effects including anti-apoptosis, anti …
(BDNF) also possesses other neuroprotective effects including anti-apoptosis, anti …
[PDF][PDF] Sestrin2 aggravates oxidative stress of neurons by decreasing the expression of Nrf2.
LL Zhang, ZJ Zhang - European Review for Medical & …, 2018 - europeanreview.org
OBJECTIVE: Oxidative injury is an essential part of the pathological changes of cerebral
ischemia-reperfusion. Sestrin2 (Sesn2), a conserved antioxidant protein, is activated under …
ischemia-reperfusion. Sestrin2 (Sesn2), a conserved antioxidant protein, is activated under …
Sestrin2 protects against traumatic brain injury by reinforcing the activation of Nrf2 signaling
X Liu, M Li, J Zhu, W Huang… - Human & Experimental …, 2021 - journals.sagepub.com
Sestrin2 (SESN2) is stress-inducible protein that confers cytoprotective effects against
various noxious stimuli. Accumulating evidence has documented that SESN2 has potent anti …
various noxious stimuli. Accumulating evidence has documented that SESN2 has potent anti …
c-Jun-dependent sulfiredoxin induction mediates BDNF protection against mitochondrial inhibition in rat cortical neurons
CL Wu, JH Yin, CS Hwang, SD Chen, DY Yang… - Neurobiology of …, 2012 - Elsevier
In current study, we tested the hypothesis that c-Jun-dependent sulfiredoxin expression
mediates protective effects of brain-derived neurotrophic factor (BDNF) against neurotoxicity …
mediates protective effects of brain-derived neurotrophic factor (BDNF) against neurotoxicity …
Sestrin2 silencing exacerbates cerebral ischemia/reperfusion injury by decreasing mitochondrial biogenesis through the AMPK/PGC-1α pathway in rats
L Li, L Xiao, Y Hou, Q He, J Zhu, Y Li, J Wu, J Zhao… - Scientific Reports, 2016 - nature.com
Abstract Sestrin2 (Sesn2) exerts neuroprotective properties in some neurodegenerative
diseases. However, the role of Sesn2 in stroke is unclear. The AMP-activated protein …
diseases. However, the role of Sesn2 in stroke is unclear. The AMP-activated protein …
Sinomenine Protects PC12 Neuronal Cells against H2O2-induced Cytotoxicity and Oxidative Stress via a ROS-dependent Up-regulation of Endogenous Antioxidant …
H Fan, Q Shu, X Guan, J Zhao, J Yan, X Li, J Liu… - Cellular and molecular …, 2017 - Springer
Sinomenine (SN), a purified alkaloid from Chinese herb Sinomenium acutum that was used
preferentially in the treatment of rheumatoid diseases, has exerted neuroprotective effects …
preferentially in the treatment of rheumatoid diseases, has exerted neuroprotective effects …
Sestrin1 exerts a cytoprotective role against oxygen-glucose deprivation/reoxygenation-induced neuronal injury by potentiating Nrf2 activation via the modulation of …
F Yang, R Chen - Brain Research, 2021 - Elsevier
Abstract Sestrin1 (Sesn1) acts as a stress-inducible protein that performs a remarkable
cytoprotective function upon diverse cellular stresses. However, whether Sesn1 exerts a …
cytoprotective function upon diverse cellular stresses. However, whether Sesn1 exerts a …
Brain‐derived neurotrophic factor protects neurons by stimulating mitochondrial function through protein kinase A
M Swain, S K. Soman, K Tapia… - Journal of …, 2023 - Wiley Online Library
Brain‐derived neurotrophic factor (BDNF) stimulates dendrite outgrowth and synaptic
plasticity by activating downstream protein kinase A (PKA) signaling. Recently, BDNF has …
plasticity by activating downstream protein kinase A (PKA) signaling. Recently, BDNF has …
Trilobatin protects against oxidative injury in neuronal PC12 cells through regulating mitochondrial ROS homeostasis mediated by AMPK/Nrf2/Sirt3 signaling pathway
J Gao, S Liu, F Xu, Y Liu, C Lv, Y Deng… - Frontiers in Molecular …, 2018 - frontiersin.org
Oxidative stress-induced neuronal cell damage is a crucial factor in the pathogenesis of
mitochondria-associated neurological diseases. Therefore, elimination of overproduction of …
mitochondria-associated neurological diseases. Therefore, elimination of overproduction of …