Chondroitin sulfate and chitosan-coated liposomes as a novel delivery system for betanin: Preparation, characterization and in vitro digestion behavior

Y Guan, Y Ning, Z Xu, C Zhou, Z Zhao - International Journal of Biological …, 2024 - Elsevier
Betanin, a water-soluble pigment known for its high bioactivity, is hindered by pH and
temperature sensitivity, weak ionic strength, and low bioavailability. In this study …

Chitosan-coated nanoliposomes for efficient delivery of betanin with enhanced stability and bioavailability

S Liu, J Lian, Z Xu, Y Ning, M Shi, Z Zhao, Z Zhang - Food Hydrocolloids, 2022 - Elsevier
Betanin is a high-value health-promoting food ingredient. However, the bioavailability of
betanin is constrained by its low stability. In this study, for the first time, betanin was …

Coating of betanin and carvone Co-loaded nanoliposomes with synthesized cationic inulin: A strategy for enhancing the stability and bioavailability

S Amjadi, H Almasi, H Hamishehkar, MA Khaledabad… - Food Chemistry, 2022 - Elsevier
Betanin (BET) and carvone (CAR) as antioxidant and antibacterial compounds were co-
loaded in the coated nanoliposomes (NLPs) with cationic inulin to improve their stability and …

Enhancement of therapeutic efficacy of betanin for diabetes treatment by liposomal nanocarriers

S Amjadi, MM Abbasi, B Shokouhi, M Ghorbani… - Journal of functional …, 2019 - Elsevier
Betanin is a bioactive compound with a high antioxidant activity and therapeutic potential.
However, incomplete oral absorption and low stability of betanin limit its application. To …

Synthesis, structural characterization and in vitro pharmacological properties of betanin-encapsulated chitosan nanoparticles

O Shafqat, Z Rehman, MM Shah, SHB Ali… - Chemico-Biological …, 2023 - Elsevier
Betanin, a natural food color and the only betalain, is approved for use in pharmaceutical
and food industries as natural antioxidative and preservative agent, respectively. However …

Chitosan-Based Nanogels Designed for Betanin-Rich Beetroot Extract Transport: Physicochemical and Biological Aspects

R Silva Nieto, C Samaniego López, MA Moretton… - Polymers, 2023 - mdpi.com
Nanotechnology has emerged as a possible solution to improve phytochemicals' limitations.
The objective of the present study was to encapsulate beetroot extract (BR Ext) within a …

Improvement in the stability of betanin by liposomal nanocarriers: Its application in gummy candy as a food model

S Amjadi, M Ghorbani, H Hamishehkar… - Food chemistry, 2018 - Elsevier
Betanin is a red food pigment with health beneficial effects. Despite interest in the use of
betanin, low bioaccessibility and oxidation limit its application. To overcome these …

Betanin loaded nanocarriers based on quinoa seed 11S globulin. Impact on the protein structure and antioxidant activity

JH Martinez, F Velazquez, HP Burrieza, KD Martinez… - Food …, 2019 - Elsevier
The objective of the present contribution was to design and characterize betanin (Bt) loaded
11S quinoa seed protein nanovehicles. 11S was isolated from quinoa seed floor. Protein …

Characteristics and properties of the quaternary ammonium-functionalized micron chitosan modified by zinc citrate chelates for encapsulation of betanin

J Xu, J Lian, L You, Z Zhao - Colloids and Surfaces B: Biointerfaces, 2022 - Elsevier
Betanin is a high-value bioactive ingredient, but its application in the food industry is limited
by its easy degradability. Encapsulation can improve the stability of various ingredients and …

Chitosan-coated nano-liposomes for the oral delivery of berberine hydrochloride

TX Nguyen, L Huang, L Liu, AME Abdalla… - Journal of Materials …, 2014 - pubs.rsc.org
Berberine hydrochloride (BH) possesses various pharmacological properties including
anticancer; unfortunately, it has low oral bioavailability and potential side effects for its …