We developed new gossypol (Gos)-based glycoconjugates through dehydration
condensation of native Gos and chemically modified glycosides having aminooxy groups …

Novel glycosidic gossypol analogs, 7, 7′-gossypol diglucoside tetraacetate GS1, 6, 7′-
gossypol diglucoside tetraacetate GS2, 7, 7′-gossypol diglycoside GS1′, 6, 7′-gossypol …

Gossypol, a natural product extracted from the seed, roots, and stem of cotton, was initially
used as a male contraceptive but was subsequently investigated as a novel antitumor agent …

Natural steroidal glycosides containing α-l-rhamnopyranosyl-(1→ 4)-[α-l-rhamnopyranosyl-
(1→ 2)]-β-d-glucopyranose (chacotriose) at the oligosaccharide moiety exhibit anti-cancer …

Gossypol as a natural occurring polyphenol has been studied in a wide range of therapeutic
contexts for a long time. The chemical modifications on gossypol were limited due to the …

Gossypol is a naturally occurring, highly colored yellow pigment indigenous to the small
intercellular pigment glands of the cotton plant genus Gossypium, which is proposed to be …

Abstract Gossypol [(2, 2′-binaphthalene)-8, 8′-dicarboxaldehyde-1, 1′, 6, 6′, 7, 7′-
hexahydroxy-5, 5′-diisopropyl-3, 3′-dimethyl] 1a is a naturally occurring compound …

Using orthogonal protection–deprotection glycosylation strategy, a series of diosgenyl
glycosides with same of monosaccharides component but different in sequence were …

Many different glycoconjugates, including saponins (eg, hellebrin) and anthracyclines (eg,
doxorubicin), are known to display cytotoxic activities. In recent work, we have developed …

The major hurdle to the success of many potent chemotherapeutic drugs is the lack of
stability of their active form suited for a particular mode of action. Efforts are needed to …